Comprehensive analysis of systemically disseminated ST8/non-USA300 type community-acquired methicillin-resistant Staphylococcus aureus infection

Hideharu Hagiya, Junzo Hisatsune, Taro Kojima, Sumiko Shiota, Hiromichi Naito, Shingo Hagioka, Naoki Morimoto, Fumio Otsuka, Motoyuki Sugai

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is genetically heterogeneous and various genotypes are spreading worldwide. We herein report a case of systematically disseminated Japan-intrinsic CA-MRSA infection that was successfully treated. A genetically identical single strain was isolated from a total of 11 different parts of the patient's body, and the pathogen was found to be multilocus sequence type 8, staphylococcal cassette chromosome mec IV, coagulase type III and negative for both Panton-Valentine leukocidin and arginine catabolic mobile element. The epidemiology and pathogenicity of the Japan-intrinsic CA-MRSA strain remain unknown, and further investigation of this life-threatening organism is warranted.

Original languageEnglish
Pages (from-to)907-912
Number of pages6
JournalInternal Medicine
Volume53
Issue number8
DOIs
Publication statusPublished - 2014

Fingerprint

Methicillin-Resistant Staphylococcus aureus
Japan
Infection
Coagulase
Human Body
Virulence
Arginine
Epidemiology
Chromosomes
Genotype

Keywords

  • Community-acquired methicillin-resistant staphylococcus aureus
  • Multilocus sequence type 8
  • Sepsis
  • Toxic shock syndrome
  • USA300

ASJC Scopus subject areas

  • Internal Medicine
  • Medicine(all)

Cite this

Comprehensive analysis of systemically disseminated ST8/non-USA300 type community-acquired methicillin-resistant Staphylococcus aureus infection. / Hagiya, Hideharu; Hisatsune, Junzo; Kojima, Taro; Shiota, Sumiko; Naito, Hiromichi; Hagioka, Shingo; Morimoto, Naoki; Otsuka, Fumio; Sugai, Motoyuki.

In: Internal Medicine, Vol. 53, No. 8, 2014, p. 907-912.

Research output: Contribution to journalArticle

Hagiya, Hideharu ; Hisatsune, Junzo ; Kojima, Taro ; Shiota, Sumiko ; Naito, Hiromichi ; Hagioka, Shingo ; Morimoto, Naoki ; Otsuka, Fumio ; Sugai, Motoyuki. / Comprehensive analysis of systemically disseminated ST8/non-USA300 type community-acquired methicillin-resistant Staphylococcus aureus infection. In: Internal Medicine. 2014 ; Vol. 53, No. 8. pp. 907-912.
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