Abstract
Using a competitive nitric oxide (NO)-trapping method between Fe-dithiocarbamate (DTC) complexes and liposome-encapsulated 2-[4-trimethylammonio]-4,4,5,5-tetramethyl-imidazoline-1-oxyl 3-oxide (TMAPTIO), NO-trapping rates of Fe-DTC complexes in the presence of phosphatidylcholine liposomes were quantified for five kinds of Fe-DTC complexes. We investigated how the DTC ligand structure influences the NO-trapping rates of Fe-DTC complexes. The negatively charged liposomes give a higher NO-trapping rate of Fe-DTC complexes than do the positively charged ones, suggesting that the presence of a charge on the liposome surface affects the NO-trapping rate processes of Fe-DTC complexes. In addition, on the basis of the pressure dependence experiments for the competitive reaction, we evaluated the difference in activation volumes between the NO-trapping reactions by Fe-DTC complexes and TMA-PTIO, which allowed us to consider possible reaction mechanisms for the NO-trapping processes.
| Original language | English |
|---|---|
| Pages (from-to) | 261-272 |
| Number of pages | 12 |
| Journal | Applied Magnetic Resonance |
| Volume | 39 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2010 |
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ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
Cite this
Competitive Trapping of Nitric Oxide (NO) Between Fe(III)-dithiocarbamate Complex and Liposome-encapsulated Trimethylammonio-PTIO : Effects of Ligand Structure, Charge on Liposome Surface, and External Pressure on NO-trapping Rates. / Sueishi, Yoshimi; Iwamoto, Shinpei.
In: Applied Magnetic Resonance, Vol. 39, No. 3, 2010, p. 261-272.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Competitive Trapping of Nitric Oxide (NO) Between Fe(III)-dithiocarbamate Complex and Liposome-encapsulated Trimethylammonio-PTIO
T2 - Effects of Ligand Structure, Charge on Liposome Surface, and External Pressure on NO-trapping Rates
AU - Sueishi, Yoshimi
AU - Iwamoto, Shinpei
PY - 2010
Y1 - 2010
N2 - Using a competitive nitric oxide (NO)-trapping method between Fe-dithiocarbamate (DTC) complexes and liposome-encapsulated 2-[4-trimethylammonio]-4,4,5,5-tetramethyl-imidazoline-1-oxyl 3-oxide (TMAPTIO), NO-trapping rates of Fe-DTC complexes in the presence of phosphatidylcholine liposomes were quantified for five kinds of Fe-DTC complexes. We investigated how the DTC ligand structure influences the NO-trapping rates of Fe-DTC complexes. The negatively charged liposomes give a higher NO-trapping rate of Fe-DTC complexes than do the positively charged ones, suggesting that the presence of a charge on the liposome surface affects the NO-trapping rate processes of Fe-DTC complexes. In addition, on the basis of the pressure dependence experiments for the competitive reaction, we evaluated the difference in activation volumes between the NO-trapping reactions by Fe-DTC complexes and TMA-PTIO, which allowed us to consider possible reaction mechanisms for the NO-trapping processes.
AB - Using a competitive nitric oxide (NO)-trapping method between Fe-dithiocarbamate (DTC) complexes and liposome-encapsulated 2-[4-trimethylammonio]-4,4,5,5-tetramethyl-imidazoline-1-oxyl 3-oxide (TMAPTIO), NO-trapping rates of Fe-DTC complexes in the presence of phosphatidylcholine liposomes were quantified for five kinds of Fe-DTC complexes. We investigated how the DTC ligand structure influences the NO-trapping rates of Fe-DTC complexes. The negatively charged liposomes give a higher NO-trapping rate of Fe-DTC complexes than do the positively charged ones, suggesting that the presence of a charge on the liposome surface affects the NO-trapping rate processes of Fe-DTC complexes. In addition, on the basis of the pressure dependence experiments for the competitive reaction, we evaluated the difference in activation volumes between the NO-trapping reactions by Fe-DTC complexes and TMA-PTIO, which allowed us to consider possible reaction mechanisms for the NO-trapping processes.
UR - http://www.scopus.com/inward/record.url?scp=77957271413&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77957271413&partnerID=8YFLogxK
U2 - 10.1007/s00723-010-0154-8
DO - 10.1007/s00723-010-0154-8
M3 - Article
AN - SCOPUS:77957271413
VL - 39
SP - 261
EP - 272
JO - Applied Magnetic Resonance
JF - Applied Magnetic Resonance
SN - 0937-9347
IS - 3
ER -