Abstract
Background: The valuation study of the five-level version of the EuroQol five-dimensional questionnaire (EQ-5D-5L) involved composite time trade-off (cTTO) and a discrete choice experiment (DCE). The DCE scores must be anchored to the quality-of-life scale from 0 (death) to 1 (full health). Nevertheless, the characteristics of the statistical methods used for converting the EQ-5D-5L DCE results by using TTO information are not yet clearly known. Objectives: To present the Japanese DCE value set of the EQ-5D-5L and compare three methods for converting latent DCE values. Methods: The survey sampled the general population at five locations in Japan. 1098 respondents were stratified by age and sex. To obtain and compare the value sets of the EQ-5D-5L, the cTTO and DCE data were analyzed by a linear mixed model and conditional logit, respectively. The DCE scores were converted to the quality-of-life scale by anchoring to the worst state using cTTO, mapping DCE onto cTTO, and a hybrid model. Results: The data from 1026 respondents were analyzed. All the coefficients in the cTTO and DCE value sets were consistent throughout all the analyses. Compared with the cTTO algorithm, the mapping and hybrid methods yielded very similar scoring coefficients. The hybrid model results, however, produced a lower root mean square error and fewer health states with errors exceeding 0.05 than did the other models. The DCE anchored to the worst state overestimated the cTTO scores of almost all the health states. Conclusions: Japanese value sets based on DCE were demonstrated. On comparing the observed cTTO scores, we found that the hybrid model was slightly superior to the simpler methods, including the TTO model.
| Original language | English |
|---|---|
| Journal | Value in Health |
| DOIs | |
| Publication status | Accepted/In press - 2016 |
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Keywords
- Discrete choice experiment (DCE)
- EQ-5D-5L
- Preference
- Time trade-off (TTO)
ASJC Scopus subject areas
- Health Policy
- Public Health, Environmental and Occupational Health
Cite this
Comparison of Value Set Based on DCE and/or TTO Data : Scoring for EQ-5D-5L Health States in Japan. / Shiroiwa, Takeru; Ikeda, Shunya; Noto, Shinichi; Igarashi, Ataru; Fukuda, Takashi; Saito, Shinya; Shimozuma, Kojiro.
In: Value in Health, 2016.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comparison of Value Set Based on DCE and/or TTO Data
T2 - Scoring for EQ-5D-5L Health States in Japan
AU - Shiroiwa, Takeru
AU - Ikeda, Shunya
AU - Noto, Shinichi
AU - Igarashi, Ataru
AU - Fukuda, Takashi
AU - Saito, Shinya
AU - Shimozuma, Kojiro
PY - 2016
Y1 - 2016
N2 - Background: The valuation study of the five-level version of the EuroQol five-dimensional questionnaire (EQ-5D-5L) involved composite time trade-off (cTTO) and a discrete choice experiment (DCE). The DCE scores must be anchored to the quality-of-life scale from 0 (death) to 1 (full health). Nevertheless, the characteristics of the statistical methods used for converting the EQ-5D-5L DCE results by using TTO information are not yet clearly known. Objectives: To present the Japanese DCE value set of the EQ-5D-5L and compare three methods for converting latent DCE values. Methods: The survey sampled the general population at five locations in Japan. 1098 respondents were stratified by age and sex. To obtain and compare the value sets of the EQ-5D-5L, the cTTO and DCE data were analyzed by a linear mixed model and conditional logit, respectively. The DCE scores were converted to the quality-of-life scale by anchoring to the worst state using cTTO, mapping DCE onto cTTO, and a hybrid model. Results: The data from 1026 respondents were analyzed. All the coefficients in the cTTO and DCE value sets were consistent throughout all the analyses. Compared with the cTTO algorithm, the mapping and hybrid methods yielded very similar scoring coefficients. The hybrid model results, however, produced a lower root mean square error and fewer health states with errors exceeding 0.05 than did the other models. The DCE anchored to the worst state overestimated the cTTO scores of almost all the health states. Conclusions: Japanese value sets based on DCE were demonstrated. On comparing the observed cTTO scores, we found that the hybrid model was slightly superior to the simpler methods, including the TTO model.
AB - Background: The valuation study of the five-level version of the EuroQol five-dimensional questionnaire (EQ-5D-5L) involved composite time trade-off (cTTO) and a discrete choice experiment (DCE). The DCE scores must be anchored to the quality-of-life scale from 0 (death) to 1 (full health). Nevertheless, the characteristics of the statistical methods used for converting the EQ-5D-5L DCE results by using TTO information are not yet clearly known. Objectives: To present the Japanese DCE value set of the EQ-5D-5L and compare three methods for converting latent DCE values. Methods: The survey sampled the general population at five locations in Japan. 1098 respondents were stratified by age and sex. To obtain and compare the value sets of the EQ-5D-5L, the cTTO and DCE data were analyzed by a linear mixed model and conditional logit, respectively. The DCE scores were converted to the quality-of-life scale by anchoring to the worst state using cTTO, mapping DCE onto cTTO, and a hybrid model. Results: The data from 1026 respondents were analyzed. All the coefficients in the cTTO and DCE value sets were consistent throughout all the analyses. Compared with the cTTO algorithm, the mapping and hybrid methods yielded very similar scoring coefficients. The hybrid model results, however, produced a lower root mean square error and fewer health states with errors exceeding 0.05 than did the other models. The DCE anchored to the worst state overestimated the cTTO scores of almost all the health states. Conclusions: Japanese value sets based on DCE were demonstrated. On comparing the observed cTTO scores, we found that the hybrid model was slightly superior to the simpler methods, including the TTO model.
KW - Discrete choice experiment (DCE)
KW - EQ-5D-5L
KW - Preference
KW - Time trade-off (TTO)
UR - http://www.scopus.com/inward/record.url?scp=84964577643&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84964577643&partnerID=8YFLogxK
U2 - 10.1016/j.jval.2016.03.1834
DO - 10.1016/j.jval.2016.03.1834
M3 - Article
C2 - 27565282
AN - SCOPUS:84964577643
JO - Value in Health
JF - Value in Health
SN - 1098-3015
ER -