Comparison of the interfacial properties of span 80 vesicle, w/o emulsions and liposomes

Keita Hayashi, Hiroshi Umakoshi, Toshinori Shimanouchi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Vesicles composed of sorbitan monooleate (Span 80) were prepared by a two-step emulsification method. The water-in-oil (W/O) emulsions generated in the first step of emulsification exhibited a quite dynamic and large hydrophobic difference between water and hexane. A subsequent emulsification yielded the vesicles with a fluid and flexible interface, as compared with that of liposomes. It was furthermore demonstrated that the two-step emulsification method has the advantage of the introduction of a PEG layer into the outer surface of the vesicles, while retaining the membrane properties of the vesicles.

Original languageEnglish
Pages (from-to)191-199
Number of pages9
JournalSolvent Extraction Research and Development
Volume21
Issue number2
DOIs
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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