Abstract
Vesicles composed of sorbitan monooleate (Span 80) were prepared by a two-step emulsification method. The water-in-oil (W/O) emulsions generated in the first step of emulsification exhibited a quite dynamic and large hydrophobic difference between water and hexane. A subsequent emulsification yielded the vesicles with a fluid and flexible interface, as compared with that of liposomes. It was furthermore demonstrated that the two-step emulsification method has the advantage of the introduction of a PEG layer into the outer surface of the vesicles, while retaining the membrane properties of the vesicles.
| Original language | English |
|---|---|
| Pages (from-to) | 191-199 |
| Number of pages | 9 |
| Journal | Solvent Extraction Research and Development |
| Volume | 21 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2014 |
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ASJC Scopus subject areas
- Chemistry(all)
- Chemical Engineering(all)
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Comparison of the interfacial properties of span 80 vesicle, w/o emulsions and liposomes. / Hayashi, Keita; Umakoshi, Hiroshi; Shimanouchi, Toshinori.
In: Solvent Extraction Research and Development, Vol. 21, No. 2, 2014, p. 191-199.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comparison of the interfacial properties of span 80 vesicle, w/o emulsions and liposomes
AU - Hayashi, Keita
AU - Umakoshi, Hiroshi
AU - Shimanouchi, Toshinori
PY - 2014
Y1 - 2014
N2 - Vesicles composed of sorbitan monooleate (Span 80) were prepared by a two-step emulsification method. The water-in-oil (W/O) emulsions generated in the first step of emulsification exhibited a quite dynamic and large hydrophobic difference between water and hexane. A subsequent emulsification yielded the vesicles with a fluid and flexible interface, as compared with that of liposomes. It was furthermore demonstrated that the two-step emulsification method has the advantage of the introduction of a PEG layer into the outer surface of the vesicles, while retaining the membrane properties of the vesicles.
AB - Vesicles composed of sorbitan monooleate (Span 80) were prepared by a two-step emulsification method. The water-in-oil (W/O) emulsions generated in the first step of emulsification exhibited a quite dynamic and large hydrophobic difference between water and hexane. A subsequent emulsification yielded the vesicles with a fluid and flexible interface, as compared with that of liposomes. It was furthermore demonstrated that the two-step emulsification method has the advantage of the introduction of a PEG layer into the outer surface of the vesicles, while retaining the membrane properties of the vesicles.
UR - http://www.scopus.com/inward/record.url?scp=84901945171&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84901945171&partnerID=8YFLogxK
U2 - 10.15261/serdj.21.191
DO - 10.15261/serdj.21.191
M3 - Article
AN - SCOPUS:84901945171
VL - 21
SP - 191
EP - 199
JO - Solvent Extraction Research and Development
JF - Solvent Extraction Research and Development
SN - 1341-7215
IS - 2
ER -