Abstract
Vesicles composed of sorbitan monooleate (Span 80) were prepared by a two-step emulsification method. The water-in-oil (W/O) emulsions generated in the first step of emulsification exhibited a quite dynamic and large hydrophobic difference between water and hexane. A subsequent emulsification yielded the vesicles with a fluid and flexible interface, as compared with that of liposomes. It was furthermore demonstrated that the two-step emulsification method has the advantage of the introduction of a PEG layer into the outer surface of the vesicles, while retaining the membrane properties of the vesicles.
| Original language | English |
|---|---|
| Pages (from-to) | 191-199 |
| Number of pages | 9 |
| Journal | Solvent Extraction Research and Development |
| Volume | 21 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2014 |
ASJC Scopus subject areas
- Chemistry(all)
- Chemical Engineering(all)
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Hayashi, K., Umakoshi, H., & Shimanouchi, T. (2014). Comparison of the interfacial properties of span 80 vesicle, w/o emulsions and liposomes. Solvent Extraction Research and Development, 21(2), 191-199. https://doi.org/10.15261/serdj.21.191