Comparison of contamination between conventional three-way stopcock and needleless injection device

A randomized controlled trial

Jun Oto, Masaji Nishimura, Hiroshi Morimatsu, Hiroshi Katayama, Mutsuo Onodera, Hideo Takahashi, Jun Takezawa

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background: Intraluminal contamination of catheter hubs has been recognized as the most frequent cause of catheter-related blood stream infections. We have investigated the efficacy of a new hub device, Planecta SC® (PNSC), in preventing endoluminal catheter contamination, compared to a conventional three-way stopcock. Material/Methods: Adults patients requiring an intravascular catheter placement for at least 48 hours in intensive care units were randomly assigned to receive either the infusion device with the newly designed hub, PNSC (P group, n=89), or with a conventional three-way stopcock (C group, n=73). To evaluate intraluminal contamination, we examined the bacteria isolated in the inline bacterial filters which were attached to downstream of the injection ports. In addition to the clinical study, we conducted a bench study to investigate if use of protection caps or strict disinfection technique prevented intraluminal contamination with this new needleless connector. Results: The incidence of bacterial contamination was not significantly different between the groups (P group 9/89 (10.1%) vs. C group 6/73 (8.2%), P=0.79). There was no correlation between the numbers of injections, duration of the use of the device or the microbial contamination rate. In the bench study, protection caps and disinfection technique significantly decreased microbial transfer from the hub to the fluid space. Conclusions: We concluded that the use of the new hub device did not reduce endoluminal bacterial contamination rate in comparison with that of a three way stopcock. Intraluminal bacterial contamination may be reduced by either strict disinfection technique or when a protection cap is use.

Original languageEnglish
JournalMedical Science Monitor
Volume13
Issue number10
Publication statusPublished - Oct 2007

Fingerprint

Disinfection
Catheters
Randomized Controlled Trials
Equipment and Supplies
Injections
Intensive Care Units
Bacteria
Incidence
Infection

Keywords

  • Catheter contamination
  • Needleless device
  • Three-way stopcock

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Comparison of contamination between conventional three-way stopcock and needleless injection device : A randomized controlled trial. / Oto, Jun; Nishimura, Masaji; Morimatsu, Hiroshi; Katayama, Hiroshi; Onodera, Mutsuo; Takahashi, Hideo; Takezawa, Jun.

In: Medical Science Monitor, Vol. 13, No. 10, 10.2007.

Research output: Contribution to journalArticle

Oto, Jun ; Nishimura, Masaji ; Morimatsu, Hiroshi ; Katayama, Hiroshi ; Onodera, Mutsuo ; Takahashi, Hideo ; Takezawa, Jun. / Comparison of contamination between conventional three-way stopcock and needleless injection device : A randomized controlled trial. In: Medical Science Monitor. 2007 ; Vol. 13, No. 10.
@article{fb54ce571f304c2291240665ef987c12,
title = "Comparison of contamination between conventional three-way stopcock and needleless injection device: A randomized controlled trial",
abstract = "Background: Intraluminal contamination of catheter hubs has been recognized as the most frequent cause of catheter-related blood stream infections. We have investigated the efficacy of a new hub device, Planecta SC{\circledR} (PNSC), in preventing endoluminal catheter contamination, compared to a conventional three-way stopcock. Material/Methods: Adults patients requiring an intravascular catheter placement for at least 48 hours in intensive care units were randomly assigned to receive either the infusion device with the newly designed hub, PNSC (P group, n=89), or with a conventional three-way stopcock (C group, n=73). To evaluate intraluminal contamination, we examined the bacteria isolated in the inline bacterial filters which were attached to downstream of the injection ports. In addition to the clinical study, we conducted a bench study to investigate if use of protection caps or strict disinfection technique prevented intraluminal contamination with this new needleless connector. Results: The incidence of bacterial contamination was not significantly different between the groups (P group 9/89 (10.1{\%}) vs. C group 6/73 (8.2{\%}), P=0.79). There was no correlation between the numbers of injections, duration of the use of the device or the microbial contamination rate. In the bench study, protection caps and disinfection technique significantly decreased microbial transfer from the hub to the fluid space. Conclusions: We concluded that the use of the new hub device did not reduce endoluminal bacterial contamination rate in comparison with that of a three way stopcock. Intraluminal bacterial contamination may be reduced by either strict disinfection technique or when a protection cap is use.",
keywords = "Catheter contamination, Needleless device, Three-way stopcock",
author = "Jun Oto and Masaji Nishimura and Hiroshi Morimatsu and Hiroshi Katayama and Mutsuo Onodera and Hideo Takahashi and Jun Takezawa",
year = "2007",
month = "10",
language = "English",
volume = "13",
journal = "Medical Science Monitor",
issn = "1234-1010",
publisher = "International Scientific Literature Inc.",
number = "10",

}

TY - JOUR

T1 - Comparison of contamination between conventional three-way stopcock and needleless injection device

T2 - A randomized controlled trial

AU - Oto, Jun

AU - Nishimura, Masaji

AU - Morimatsu, Hiroshi

AU - Katayama, Hiroshi

AU - Onodera, Mutsuo

AU - Takahashi, Hideo

AU - Takezawa, Jun

PY - 2007/10

Y1 - 2007/10

N2 - Background: Intraluminal contamination of catheter hubs has been recognized as the most frequent cause of catheter-related blood stream infections. We have investigated the efficacy of a new hub device, Planecta SC® (PNSC), in preventing endoluminal catheter contamination, compared to a conventional three-way stopcock. Material/Methods: Adults patients requiring an intravascular catheter placement for at least 48 hours in intensive care units were randomly assigned to receive either the infusion device with the newly designed hub, PNSC (P group, n=89), or with a conventional three-way stopcock (C group, n=73). To evaluate intraluminal contamination, we examined the bacteria isolated in the inline bacterial filters which were attached to downstream of the injection ports. In addition to the clinical study, we conducted a bench study to investigate if use of protection caps or strict disinfection technique prevented intraluminal contamination with this new needleless connector. Results: The incidence of bacterial contamination was not significantly different between the groups (P group 9/89 (10.1%) vs. C group 6/73 (8.2%), P=0.79). There was no correlation between the numbers of injections, duration of the use of the device or the microbial contamination rate. In the bench study, protection caps and disinfection technique significantly decreased microbial transfer from the hub to the fluid space. Conclusions: We concluded that the use of the new hub device did not reduce endoluminal bacterial contamination rate in comparison with that of a three way stopcock. Intraluminal bacterial contamination may be reduced by either strict disinfection technique or when a protection cap is use.

AB - Background: Intraluminal contamination of catheter hubs has been recognized as the most frequent cause of catheter-related blood stream infections. We have investigated the efficacy of a new hub device, Planecta SC® (PNSC), in preventing endoluminal catheter contamination, compared to a conventional three-way stopcock. Material/Methods: Adults patients requiring an intravascular catheter placement for at least 48 hours in intensive care units were randomly assigned to receive either the infusion device with the newly designed hub, PNSC (P group, n=89), or with a conventional three-way stopcock (C group, n=73). To evaluate intraluminal contamination, we examined the bacteria isolated in the inline bacterial filters which were attached to downstream of the injection ports. In addition to the clinical study, we conducted a bench study to investigate if use of protection caps or strict disinfection technique prevented intraluminal contamination with this new needleless connector. Results: The incidence of bacterial contamination was not significantly different between the groups (P group 9/89 (10.1%) vs. C group 6/73 (8.2%), P=0.79). There was no correlation between the numbers of injections, duration of the use of the device or the microbial contamination rate. In the bench study, protection caps and disinfection technique significantly decreased microbial transfer from the hub to the fluid space. Conclusions: We concluded that the use of the new hub device did not reduce endoluminal bacterial contamination rate in comparison with that of a three way stopcock. Intraluminal bacterial contamination may be reduced by either strict disinfection technique or when a protection cap is use.

KW - Catheter contamination

KW - Needleless device

KW - Three-way stopcock

UR - http://www.scopus.com/inward/record.url?scp=35548990960&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35548990960&partnerID=8YFLogxK

M3 - Article

VL - 13

JO - Medical Science Monitor

JF - Medical Science Monitor

SN - 1234-1010

IS - 10

ER -