Comparative uptake behavior of trace elements in adult and suckling rat lens

Tomohiro Nabekura; Takeshi Minami; Rieko Hirunuma; Shuichi Enomoto; Ryohei Hori; Yoshimasa Ito

doi:10.1016/S0300-483X(01)00384-5

Comparative uptake behavior of trace elements in adult and suckling rat lens

Tomohiro Nabekura, Takeshi Minami, Rieko Hirunuma, Shuichi Enomoto, Ryohei Hori, Yoshimasa Ito

Faculty of Pharmaceutical Sciences

Research output: Contribution to journal › Article

4 Citations (Scopus)

Abstract

The multitracer technique was applied to the determination of the uptake of trace elements in the lenses of adult and suckling rats to investigate the transport mechanisms of trace elements during developmental maturation. Be, Sc, V, Mn, Fe, Co, Zn, As, Se, Rb, Sr, Y, Zr, Ru and Rh accumulate in adult and suckling rat lenses. The rates of uptake of trace elements differ among each species and also differ between adult and suckling rat lenses. The uptakes of Fe and Sr are greater in adult rat lenses, while the uptakes of Se and Rb are greater in suckling rat lenses. High concentrations of Zn are transported into the lenses of both adult and suckling rats in comparison with other elements, and the content of Zn in suckling rat lens is higher than in adult lens. The present study suggests that different mechanisms depending on the stage of development act to transport trace elements into lenses.

Original language	English
Pages (from-to)	101-105
Number of pages	5
Journal	Toxicology
Volume	163
Issue number	2-3
DOIs	https://doi.org/10.1016/S0300-483X(01)00384-5
Publication status	Published - Jun 21 2001

Keywords

Crystalline lens
Multitracer
Suckling rat
Trace elements

ASJC Scopus subject areas

Toxicology

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10.1016/S0300-483X(01)00384-5

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Nabekura, T., Minami, T., Hirunuma, R., Enomoto, S., Hori, R., & Ito, Y. (2001). Comparative uptake behavior of trace elements in adult and suckling rat lens. Toxicology, 163(2-3), 101-105. https://doi.org/10.1016/S0300-483X(01)00384-5

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abstract = "The multitracer technique was applied to the determination of the uptake of trace elements in the lenses of adult and suckling rats to investigate the transport mechanisms of trace elements during developmental maturation. Be, Sc, V, Mn, Fe, Co, Zn, As, Se, Rb, Sr, Y, Zr, Ru and Rh accumulate in adult and suckling rat lenses. The rates of uptake of trace elements differ among each species and also differ between adult and suckling rat lenses. The uptakes of Fe and Sr are greater in adult rat lenses, while the uptakes of Se and Rb are greater in suckling rat lenses. High concentrations of Zn are transported into the lenses of both adult and suckling rats in comparison with other elements, and the content of Zn in suckling rat lens is higher than in adult lens. The present study suggests that different mechanisms depending on the stage of development act to transport trace elements into lenses.",

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AU - Nabekura, Tomohiro

AU - Minami, Takeshi

AU - Hirunuma, Rieko

AU - Enomoto, Shuichi

AU - Hori, Ryohei

AU - Ito, Yoshimasa

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N2 - The multitracer technique was applied to the determination of the uptake of trace elements in the lenses of adult and suckling rats to investigate the transport mechanisms of trace elements during developmental maturation. Be, Sc, V, Mn, Fe, Co, Zn, As, Se, Rb, Sr, Y, Zr, Ru and Rh accumulate in adult and suckling rat lenses. The rates of uptake of trace elements differ among each species and also differ between adult and suckling rat lenses. The uptakes of Fe and Sr are greater in adult rat lenses, while the uptakes of Se and Rb are greater in suckling rat lenses. High concentrations of Zn are transported into the lenses of both adult and suckling rats in comparison with other elements, and the content of Zn in suckling rat lens is higher than in adult lens. The present study suggests that different mechanisms depending on the stage of development act to transport trace elements into lenses.

AB - The multitracer technique was applied to the determination of the uptake of trace elements in the lenses of adult and suckling rats to investigate the transport mechanisms of trace elements during developmental maturation. Be, Sc, V, Mn, Fe, Co, Zn, As, Se, Rb, Sr, Y, Zr, Ru and Rh accumulate in adult and suckling rat lenses. The rates of uptake of trace elements differ among each species and also differ between adult and suckling rat lenses. The uptakes of Fe and Sr are greater in adult rat lenses, while the uptakes of Se and Rb are greater in suckling rat lenses. High concentrations of Zn are transported into the lenses of both adult and suckling rats in comparison with other elements, and the content of Zn in suckling rat lens is higher than in adult lens. The present study suggests that different mechanisms depending on the stage of development act to transport trace elements into lenses.

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