Color tuning in retinylidene proteins

Kota Katayama, Sivakumar Sekharan, Yuki Sudo

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Citations (Scopus)

Abstract

Retinylidene proteins (also called rhodopsins) are membrane-embedded photoreceptors that contain a vitamin A aldehyde linked to a lysine residue by a Schiff base as their light-sensing chromophore. The chromophore is surrounded by seven-transmembrane α-helices and absorbs light at different wavelengths due to differences in the electronic energy gap between its ground and excited states. The variation in the wavelength of maximal absorption (λmax: 360–620 nm) of rhodopsins arises due to interaction between the apoprotein (opsin) and the retinyl chromophore, the ‘opsin shift’. This chapter reviews the color tuning mechanisms in type-1 microbial and type-2 animal rhodopsins as revealed mainly by our experimental and theoretical studies.

Original languageEnglish
Title of host publicationOptogenetics: Light-Sensing Proteins and their Applications
PublisherSpringer Japan
Pages89-109
Number of pages21
ISBN (Print)9784431555162, 9784431555155
DOIs
Publication statusPublished - Jan 1 2015

Fingerprint

Rhodopsin
Chromophores
Opsins
Color
Tuning
Retinaldehyde
Light
Wavelength
Proteins
Apoproteins
Schiff Bases
Excited states
Ground state
Lysine
Animals
Energy gap
Theoretical Models
Membranes

Keywords

  • Color tuning
  • Color variant
  • Retinal
  • Rhodopsin
  • Visible light
  • Vitamin-A
  • Water molecule
  • π-conjugation

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Katayama, K., Sekharan, S., & Sudo, Y. (2015). Color tuning in retinylidene proteins. In Optogenetics: Light-Sensing Proteins and their Applications (pp. 89-109). Springer Japan. https://doi.org/10.1007/978-4-431-55516-2_7

Color tuning in retinylidene proteins. / Katayama, Kota; Sekharan, Sivakumar; Sudo, Yuki.

Optogenetics: Light-Sensing Proteins and their Applications. Springer Japan, 2015. p. 89-109.

Research output: Chapter in Book/Report/Conference proceedingChapter

Katayama, K, Sekharan, S & Sudo, Y 2015, Color tuning in retinylidene proteins. in Optogenetics: Light-Sensing Proteins and their Applications. Springer Japan, pp. 89-109. https://doi.org/10.1007/978-4-431-55516-2_7
Katayama K, Sekharan S, Sudo Y. Color tuning in retinylidene proteins. In Optogenetics: Light-Sensing Proteins and their Applications. Springer Japan. 2015. p. 89-109 https://doi.org/10.1007/978-4-431-55516-2_7
Katayama, Kota ; Sekharan, Sivakumar ; Sudo, Yuki. / Color tuning in retinylidene proteins. Optogenetics: Light-Sensing Proteins and their Applications. Springer Japan, 2015. pp. 89-109
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