Colony spreading in Staphylococcus aureus

Chikara Kaito, Kazuhisa Sekimizu

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

Wild-type Staphylococcus aureus rapidly expands on the surface of soft agar plates. The rates of expansion and the shapes of the resultant giant colonies were distinct for different strains of laboratory stocks and clinical isolates. The colony spreading abilities did not correlate with the biofilm-forming abilities in these strains. Insertional disruption of the dltABCD operon, which functions at the step of D-alanine addition to teichoic acids, and of the tagO gene, which is responsible for the synthesis of wall teichoic acids, decreased the colony spreading ability. The results indicate that wall teichoic acids and D-alanylation of teichoic acids are required for colony spreading.

Original languageEnglish
Pages (from-to)2553-2557
Number of pages5
JournalJournal of Bacteriology
Volume189
Issue number6
DOIs
Publication statusPublished - Mar 1 2007
Externally publishedYes

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Teichoic Acids
Staphylococcus aureus
Operon
Biofilms
Alanine
Agar
Genes

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Immunology

Cite this

Colony spreading in Staphylococcus aureus. / Kaito, Chikara; Sekimizu, Kazuhisa.

In: Journal of Bacteriology, Vol. 189, No. 6, 01.03.2007, p. 2553-2557.

Research output: Contribution to journalArticle

Kaito, Chikara ; Sekimizu, Kazuhisa. / Colony spreading in Staphylococcus aureus. In: Journal of Bacteriology. 2007 ; Vol. 189, No. 6. pp. 2553-2557.
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