Cold pressor stimulation effect on hemodynamic changes following sustained isometric contraction in human jaw-closure muscles

Y. Tsukiyama, Takuo Kuboki, G. T. Clark

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

It is postulated that an altered adrenergic response pattern may be associated with chronic muscle pain states. To evaluate this hypothesis, one must fully understand the effect of an adrenergic activation on masticatory muscle blood flow under various conditions. This shady evaluated the effect of a 12°C cold pressor stimulation (a mild adrenergic activator), applied to the hand-forearm area, on intramuscular hemodynamics in the human masseter and temporalis muscles following a sustained isometric contraction. We assessed hemodynamics by measuring intramuscular hemoglobin concentration repeatedly, using a non-invasive near-infrared spectroscopy device. Measurements were taken before, during, and after a 30-second sustained 50% maximum voluntary contraction task. Fourteen healthy subjects, seven males and seven females, with no history of muscle pain in the masticatory system participated in this study. This protocol was repeated three times, but in the second trial, the cold pressor stimulation was applied to the subject during and for 5 min after the sustained contraction task. Repeated-measure analysis of variance performed on these data revealed that the peak hemoglobin concentration levels in the post-contraction recovery period were significantly reduced (between 13 and 14%) with cold pressor stimulation, both in the masseter (p <0.001) and in the temporalis (p <0.001) muscles. The results suggest that cold pressor stimulation produced a reduced intramuscular vasodilative response in these muscles during the immediate post-contraction period. One explanation for these results is that altering the local chemical environment of the muscle affects the adrenergic response pattern typically induced by a cold pressor stimulation.

Original languageEnglish
Pages (from-to)1727-1734
Number of pages8
JournalJournal of Dental Research
Volume78
Issue number11
Publication statusPublished - 1999

Fingerprint

Isometric Contraction
Jaw
Hemodynamics
Adrenergic Agents
Muscles
Myalgia
Hemoglobins
Stomatognathic System
Masticatory Muscles
Masseter Muscle
Near-Infrared Spectroscopy
Forearm
Chronic Pain
Analysis of Variance
Healthy Volunteers
Hand
Equipment and Supplies

Keywords

  • Cold pressor
  • Intramuscular blood flow
  • Isometric contraction
  • Masticatory muscle
  • Near-infrared spectroscopy

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Cold pressor stimulation effect on hemodynamic changes following sustained isometric contraction in human jaw-closure muscles. / Tsukiyama, Y.; Kuboki, Takuo; Clark, G. T.

In: Journal of Dental Research, Vol. 78, No. 11, 1999, p. 1727-1734.

Research output: Contribution to journalArticle

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