Cognitive and affective assessments of multiple sclerosis (MS) and neuromyelitis optica (NMO) patients utilizing computerized touch panel-type screening tests

Yuko Kawahara, Masami Ikeda, Kentaro Deguchi, Nozomi Hishikawa, Syoichiro Kono, Yoshio Omote, Kosuke Matsuzono, Toru Yamashita, Yoshio Ikeda, Koji Abe

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Results: While MS patients and normal controls (NC1, n=40) did not significantly differ in their scores from the Hasegawa dementia scale-revised (HDS-R) or the frontal assessment battery, MS patients did score significantly lower on the mini-mental state examination (MMSE). In contrast, NMO patients did not differ from the normal control group 2 (NC2, n=15) in any of the three cognitive assessments. We also examined the affective ability and found that MS patients scored significantly higher on the apathy scale (AS) compared with the NC1 group, while NMO patients scored significantly higher on the geriatric depression scale (GDS) compared with the NC2 group. Although the GDS and AS scores did not correlate with any of the cognitive assessments among MS patients, the AS scores did correlate with the MMSE and HDS-R among NMO patients. Compared with normal controls, the times to complete the flipping cards and arranging pictures games were significantly longer for MS patients but not for NMO patients.

Objective: Cognitive and affective dysfunctions are important aspects for patients with multiple sclerosis (MS) and neuromyelitis optica (NMO).

Methods: We herein examined the cognitive and affective ability in MS (n=35) and NMO (n=10) patients using computerized touch panel-type screening tests.

Conclusion: These results indicate differences between some features of cognitive and affective dysfunctions between MS and NMO patients. Computerized touch panel-type screening tests may be a more useful and sensitive tool for the cognitive assessment of MS patients than NMO patients.

Original languageEnglish
Pages (from-to)2281-2290
Number of pages10
JournalInternal Medicine
Volume53
Issue number20
DOIs
Publication statusPublished - 2014

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Neuromyelitis Optica
Touch
Multiple Sclerosis
Apathy
Aptitude
Geriatrics
Dementia
Depression

Keywords

  • Cognitive and affective functions
  • Multiple sclerosis
  • Neuromyelitis optica
  • Touch panel-type screening test

ASJC Scopus subject areas

  • Internal Medicine
  • Medicine(all)

Cite this

Cognitive and affective assessments of multiple sclerosis (MS) and neuromyelitis optica (NMO) patients utilizing computerized touch panel-type screening tests. / Kawahara, Yuko; Ikeda, Masami; Deguchi, Kentaro; Hishikawa, Nozomi; Kono, Syoichiro; Omote, Yoshio; Matsuzono, Kosuke; Yamashita, Toru; Ikeda, Yoshio; Abe, Koji.

In: Internal Medicine, Vol. 53, No. 20, 2014, p. 2281-2290.

Research output: Contribution to journalArticle

Kawahara, Yuko ; Ikeda, Masami ; Deguchi, Kentaro ; Hishikawa, Nozomi ; Kono, Syoichiro ; Omote, Yoshio ; Matsuzono, Kosuke ; Yamashita, Toru ; Ikeda, Yoshio ; Abe, Koji. / Cognitive and affective assessments of multiple sclerosis (MS) and neuromyelitis optica (NMO) patients utilizing computerized touch panel-type screening tests. In: Internal Medicine. 2014 ; Vol. 53, No. 20. pp. 2281-2290.
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AU - Kawahara, Yuko

AU - Ikeda, Masami

AU - Deguchi, Kentaro

AU - Hishikawa, Nozomi

AU - Kono, Syoichiro

AU - Omote, Yoshio

AU - Matsuzono, Kosuke

AU - Yamashita, Toru

AU - Ikeda, Yoshio

AU - Abe, Koji

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N2 - Results: While MS patients and normal controls (NC1, n=40) did not significantly differ in their scores from the Hasegawa dementia scale-revised (HDS-R) or the frontal assessment battery, MS patients did score significantly lower on the mini-mental state examination (MMSE). In contrast, NMO patients did not differ from the normal control group 2 (NC2, n=15) in any of the three cognitive assessments. We also examined the affective ability and found that MS patients scored significantly higher on the apathy scale (AS) compared with the NC1 group, while NMO patients scored significantly higher on the geriatric depression scale (GDS) compared with the NC2 group. Although the GDS and AS scores did not correlate with any of the cognitive assessments among MS patients, the AS scores did correlate with the MMSE and HDS-R among NMO patients. Compared with normal controls, the times to complete the flipping cards and arranging pictures games were significantly longer for MS patients but not for NMO patients.Objective: Cognitive and affective dysfunctions are important aspects for patients with multiple sclerosis (MS) and neuromyelitis optica (NMO).Methods: We herein examined the cognitive and affective ability in MS (n=35) and NMO (n=10) patients using computerized touch panel-type screening tests.Conclusion: These results indicate differences between some features of cognitive and affective dysfunctions between MS and NMO patients. Computerized touch panel-type screening tests may be a more useful and sensitive tool for the cognitive assessment of MS patients than NMO patients.

AB - Results: While MS patients and normal controls (NC1, n=40) did not significantly differ in their scores from the Hasegawa dementia scale-revised (HDS-R) or the frontal assessment battery, MS patients did score significantly lower on the mini-mental state examination (MMSE). In contrast, NMO patients did not differ from the normal control group 2 (NC2, n=15) in any of the three cognitive assessments. We also examined the affective ability and found that MS patients scored significantly higher on the apathy scale (AS) compared with the NC1 group, while NMO patients scored significantly higher on the geriatric depression scale (GDS) compared with the NC2 group. Although the GDS and AS scores did not correlate with any of the cognitive assessments among MS patients, the AS scores did correlate with the MMSE and HDS-R among NMO patients. Compared with normal controls, the times to complete the flipping cards and arranging pictures games were significantly longer for MS patients but not for NMO patients.Objective: Cognitive and affective dysfunctions are important aspects for patients with multiple sclerosis (MS) and neuromyelitis optica (NMO).Methods: We herein examined the cognitive and affective ability in MS (n=35) and NMO (n=10) patients using computerized touch panel-type screening tests.Conclusion: These results indicate differences between some features of cognitive and affective dysfunctions between MS and NMO patients. Computerized touch panel-type screening tests may be a more useful and sensitive tool for the cognitive assessment of MS patients than NMO patients.

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KW - Multiple sclerosis

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