Coexpression of calretinin and parvalbumin in Ruffini-like endings in the rat incisor periodontal ligament

Hiroyuki Ichikawa, David M. Jacobowitz, Tomosada Sugimoto

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

The coexpression of calretinin- (CR) and parvalbumin-immunoreactivities (irs) was examined in oro-facial tissues of the rat. Nerve fibers coexpressing these calcium-binding proteins (CaBPs) were observed in the lingual periodontal ligament of incisors but not other tissues. In the part of periodontal ligament adjacent to the alveolar bone, such nerve fibers left nerve bundles and formed bush-like endings, i.e., they ramified repeatedly and terminated with one to four twigs. An immunoelectron microscopic method indicated that these endings were identical to Ruffini- like endings. 4% of trigeminal neurons retrogradely labeled from the inferior alveolar nerve coexpressed CR- and parvalbumin-irs. The present observations suggest that the coexpression of these CaBPs may be a specific marker for low-threshold mechanoreceptors in the trigeminal ganglion.

Original languageEnglish
Pages (from-to)294-297
Number of pages4
JournalBrain Research
Volume770
Issue number1-2
DOIs
Publication statusPublished - Oct 3 1997

Fingerprint

Calbindin 2
Parvalbumins
Periodontal Ligament
Calcium-Binding Proteins
Incisor
Nerve Fibers
Mandibular Nerve
Trigeminal Ganglion
Mechanoreceptors
Tongue
Neurons
Bone and Bones

Keywords

  • Calretinin
  • Immunohistochemistry
  • Incisor
  • Parvalbumin
  • Periodontal ligament
  • Ruffini-like ending
  • Trigeminal ganglion

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Coexpression of calretinin and parvalbumin in Ruffini-like endings in the rat incisor periodontal ligament. / Ichikawa, Hiroyuki; Jacobowitz, David M.; Sugimoto, Tomosada.

In: Brain Research, Vol. 770, No. 1-2, 03.10.1997, p. 294-297.

Research output: Contribution to journalArticle

Ichikawa, Hiroyuki ; Jacobowitz, David M. ; Sugimoto, Tomosada. / Coexpression of calretinin and parvalbumin in Ruffini-like endings in the rat incisor periodontal ligament. In: Brain Research. 1997 ; Vol. 770, No. 1-2. pp. 294-297.
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