Abstract
The co-expression of vanilloid receptor 1-like receptor (VRL-1), a newly cloned capsaicin-receptor homologue, with calbindin D-28k was examined in the rat sensory ganglia. The co-expression was rare in the dorsal root, trigeminal and jugular ganglia and abundant in the petrosal and nodose ganglia. In the dorsal root ganglion, none of VRL-1-immunoreactive (ir) neuron co-expressed calbindin D-28k-immunoreactivity (ir). Of the VRL-1-ir neurons, 9 and 5% showed calbindin D-28k ir in the trigeminal and jugular ganglia, respectively. On the other hand, 35 and 63% of VRL-1-ir neurons in the petrosal and nodose ganglia, respectively, co-expressed these substances. The retrograde tracing method indicated that petrosal neurons which co-expressed VRL-1-and calbindin D-28k-ir innervated taste buds in the circumvallate papilla. The present findings may suggest that VRL-1 is associated with chemosensory functions in visceral sensory neurons.
| Original language | English |
|---|---|
| Pages (from-to) | 109-112 |
| Number of pages | 4 |
| Journal | Brain Research |
| Volume | 924 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 4 2002 |
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Keywords
- Calbindin D-28k
- Immunohistochemistry
- Petrosal ganglion
- Taste bud
- VRL-1
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Co-expression of VRL-1 and calbindin D-28k in the rat sensory ganglia. / Ichikawa, H.; Sugimoto, T.
In: Brain Research, Vol. 924, No. 1, 04.01.2002, p. 109-112.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Co-expression of VRL-1 and calbindin D-28k in the rat sensory ganglia
AU - Ichikawa, H.
AU - Sugimoto, T.
PY - 2002/1/4
Y1 - 2002/1/4
N2 - The co-expression of vanilloid receptor 1-like receptor (VRL-1), a newly cloned capsaicin-receptor homologue, with calbindin D-28k was examined in the rat sensory ganglia. The co-expression was rare in the dorsal root, trigeminal and jugular ganglia and abundant in the petrosal and nodose ganglia. In the dorsal root ganglion, none of VRL-1-immunoreactive (ir) neuron co-expressed calbindin D-28k-immunoreactivity (ir). Of the VRL-1-ir neurons, 9 and 5% showed calbindin D-28k ir in the trigeminal and jugular ganglia, respectively. On the other hand, 35 and 63% of VRL-1-ir neurons in the petrosal and nodose ganglia, respectively, co-expressed these substances. The retrograde tracing method indicated that petrosal neurons which co-expressed VRL-1-and calbindin D-28k-ir innervated taste buds in the circumvallate papilla. The present findings may suggest that VRL-1 is associated with chemosensory functions in visceral sensory neurons.
AB - The co-expression of vanilloid receptor 1-like receptor (VRL-1), a newly cloned capsaicin-receptor homologue, with calbindin D-28k was examined in the rat sensory ganglia. The co-expression was rare in the dorsal root, trigeminal and jugular ganglia and abundant in the petrosal and nodose ganglia. In the dorsal root ganglion, none of VRL-1-immunoreactive (ir) neuron co-expressed calbindin D-28k-immunoreactivity (ir). Of the VRL-1-ir neurons, 9 and 5% showed calbindin D-28k ir in the trigeminal and jugular ganglia, respectively. On the other hand, 35 and 63% of VRL-1-ir neurons in the petrosal and nodose ganglia, respectively, co-expressed these substances. The retrograde tracing method indicated that petrosal neurons which co-expressed VRL-1-and calbindin D-28k-ir innervated taste buds in the circumvallate papilla. The present findings may suggest that VRL-1 is associated with chemosensory functions in visceral sensory neurons.
KW - Calbindin D-28k
KW - Immunohistochemistry
KW - Petrosal ganglion
KW - Taste bud
KW - VRL-1
UR - http://www.scopus.com/inward/record.url?scp=0037016350&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037016350&partnerID=8YFLogxK
U2 - 10.1016/S0006-8993(01)03246-2
DO - 10.1016/S0006-8993(01)03246-2
M3 - Article
C2 - 11744001
AN - SCOPUS:0037016350
VL - 924
SP - 109
EP - 112
JO - Brain Research
JF - Brain Research
SN - 0006-8993
IS - 1
ER -