Clinico-Bacteriological Studies The Etiology Of Bacterial Prostatitis Ii. Virulence Factors Of E. Coli In Bacterial Prostatitis

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Abstract

The virulence factors of E. coli in bacterial prostatitis were studied using 59 E. coli isolated from uncomplicated prostatitis. O-antigens of prostatitis-derived E. coli belonged to some specific serotypes such as 0∼4,6,18,22 and the haemolysin production was positive in 64.4%. With regard to the fimbriae, the majority of the strains had type 1 fimbriae (81.4%). Mannose resistant (MR) fimbriae were also positive in 59.3% and both type 1 and MR fimbriae were positive in 55.9%. Among MR strains, P-fimbriated and S-fimbriated strains were present in 25.7% and 28.6%, respectively, indicating that these two MR fimbriae were not always specific for the prostatitis-derived E. coli. Although the specific adhesion of E. coli onto the human prostatic epithelium mediated by MR-fimbriae was equivocal, that mediated by type 1 fimbriae was observed clearly. Therefore, type 1 fimbriae was thought to be one of the most significant virulence factors in the pathogenesis of prostatitis caused by E. coli.

Original languageEnglish
Pages (from-to)1466-1472
Number of pages7
JournalThe Japanese Journal of Urology
Volume81
Issue number10
DOIs
Publication statusPublished - 1990

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Prostatitis
Virulence Factors
Mannose
Escherichia coli
O Antigens
Hemolysin Proteins
Epithelium

Keywords

  • bacterial prostatitis
  • E. coli
  • fimbriae

ASJC Scopus subject areas

  • Urology

Cite this

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title = "Clinico-Bacteriological Studies The Etiology Of Bacterial Prostatitis Ii. Virulence Factors Of E. Coli In Bacterial Prostatitis",
abstract = "The virulence factors of E. coli in bacterial prostatitis were studied using 59 E. coli isolated from uncomplicated prostatitis. O-antigens of prostatitis-derived E. coli belonged to some specific serotypes such as 0∼4,6,18,22 and the haemolysin production was positive in 64.4{\%}. With regard to the fimbriae, the majority of the strains had type 1 fimbriae (81.4{\%}). Mannose resistant (MR) fimbriae were also positive in 59.3{\%} and both type 1 and MR fimbriae were positive in 55.9{\%}. Among MR strains, P-fimbriated and S-fimbriated strains were present in 25.7{\%} and 28.6{\%}, respectively, indicating that these two MR fimbriae were not always specific for the prostatitis-derived E. coli. Although the specific adhesion of E. coli onto the human prostatic epithelium mediated by MR-fimbriae was equivocal, that mediated by type 1 fimbriae was observed clearly. Therefore, type 1 fimbriae was thought to be one of the most significant virulence factors in the pathogenesis of prostatitis caused by E. coli.",
keywords = "bacterial prostatitis, E. coli, fimbriae",
author = "Daisuke Yamada",
year = "1990",
doi = "10.5980/jpnjurol1989.81.1466",
language = "English",
volume = "81",
pages = "1466--1472",
journal = "Japanese Journal of Urology",
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T1 - Clinico-Bacteriological Studies The Etiology Of Bacterial Prostatitis Ii. Virulence Factors Of E. Coli In Bacterial Prostatitis

AU - Yamada, Daisuke

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N2 - The virulence factors of E. coli in bacterial prostatitis were studied using 59 E. coli isolated from uncomplicated prostatitis. O-antigens of prostatitis-derived E. coli belonged to some specific serotypes such as 0∼4,6,18,22 and the haemolysin production was positive in 64.4%. With regard to the fimbriae, the majority of the strains had type 1 fimbriae (81.4%). Mannose resistant (MR) fimbriae were also positive in 59.3% and both type 1 and MR fimbriae were positive in 55.9%. Among MR strains, P-fimbriated and S-fimbriated strains were present in 25.7% and 28.6%, respectively, indicating that these two MR fimbriae were not always specific for the prostatitis-derived E. coli. Although the specific adhesion of E. coli onto the human prostatic epithelium mediated by MR-fimbriae was equivocal, that mediated by type 1 fimbriae was observed clearly. Therefore, type 1 fimbriae was thought to be one of the most significant virulence factors in the pathogenesis of prostatitis caused by E. coli.

AB - The virulence factors of E. coli in bacterial prostatitis were studied using 59 E. coli isolated from uncomplicated prostatitis. O-antigens of prostatitis-derived E. coli belonged to some specific serotypes such as 0∼4,6,18,22 and the haemolysin production was positive in 64.4%. With regard to the fimbriae, the majority of the strains had type 1 fimbriae (81.4%). Mannose resistant (MR) fimbriae were also positive in 59.3% and both type 1 and MR fimbriae were positive in 55.9%. Among MR strains, P-fimbriated and S-fimbriated strains were present in 25.7% and 28.6%, respectively, indicating that these two MR fimbriae were not always specific for the prostatitis-derived E. coli. Although the specific adhesion of E. coli onto the human prostatic epithelium mediated by MR-fimbriae was equivocal, that mediated by type 1 fimbriae was observed clearly. Therefore, type 1 fimbriae was thought to be one of the most significant virulence factors in the pathogenesis of prostatitis caused by E. coli.

KW - bacterial prostatitis

KW - E. coli

KW - fimbriae

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