Clinical spectrum of congenital cystic disease of the lung in children

Shin Ichi Takeda, Shinichiro Miyoshi, Masayoshi Inoue, Ken Ichi Omori, Meinoshin Okumura, Hyung Eun Yoon, Masato Minami, Hikaru Matsuda

Research output: Contribution to journalArticle

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Abstract

Objectives: Congenital cystic lesions of the lung are uncommon but share similar embryologic and clinical characteristics. The purpose of this study is to review our institutional experience of congenital cystic lung disease, emphasizing the clinical spectrum of the disease related to age, and present some cases with unusual clinical manifestations. Patients: Between 1962 and 1996, 26 patients (9 females and 17 males) under 15 years old underwent evaluation and surgical treatment for congenital cystic lung disease. Seven patients were under 1 year old, and 19 were in over 1 year old. There were 13 bronchogenic pulmonary cysts, 6 pulmonary sequestrations, 4 congenital cystic adenomatoid malformations (CCAM), and 3 congenital lobar emphysemas. Results: All patients under 1 year old showed respiratory distress with mediastinal shift but no episodes of infection. In contrast, 13 of the 19 patients over 1 year old had symptoms of recurrent infection without respiratory distress. Five patients over 1 year old were entirely asymtomatic from birth. There were significant differences (P <0.05) in the frequencies of respiratory distress and infection between the two groups (χ2-test). Lobectomy was performed in 21 patients, excision in 3 patients, segmentectomy in one patient, and exploration in one patient. There was no incident of postoperative mortality or morbidity except for one patient with CCAM complicated by reexpansion lung edema. Twenty-one patients at long-term follow-up from 2 to 30 years after surgery are doing well with no subsequent limitation of physical activities due to lung resection. Conclusions: In patients under 1 year old, cystic lesions were discovered by respiratory distress; and in patients over 1 year old signs of infection were the most important clinical features. Early recognition of these relatively rare congenital cystic lung lesions would lead to the immediate, proper surgical intervention.

Original languageEnglish
Pages (from-to)11-17
Number of pages7
JournalEuropean Journal of Cardio-thoracic Surgery
Volume15
Issue number1
DOIs
Publication statusPublished - Jan 1999
Externally publishedYes

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Lung
Congenital Cystic Adenomatoid Malformation of Lung
Cystic Disease Of Lung
Respiratory Tract Infections
Bronchogenic Cyst
Bronchopulmonary Sequestration
Segmental Mastectomy
Infection
Edema
Parturition
Exercise
Morbidity
Mortality
Therapeutics

Keywords

  • Bronchopulmonary foregut malformation
  • Congenital cystic lung disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Takeda, S. I., Miyoshi, S., Inoue, M., Omori, K. I., Okumura, M., Yoon, H. E., ... Matsuda, H. (1999). Clinical spectrum of congenital cystic disease of the lung in children. European Journal of Cardio-thoracic Surgery, 15(1), 11-17. https://doi.org/10.1016/S1010-7940(98)00262-0

Clinical spectrum of congenital cystic disease of the lung in children. / Takeda, Shin Ichi; Miyoshi, Shinichiro; Inoue, Masayoshi; Omori, Ken Ichi; Okumura, Meinoshin; Yoon, Hyung Eun; Minami, Masato; Matsuda, Hikaru.

In: European Journal of Cardio-thoracic Surgery, Vol. 15, No. 1, 01.1999, p. 11-17.

Research output: Contribution to journalArticle

Takeda, SI, Miyoshi, S, Inoue, M, Omori, KI, Okumura, M, Yoon, HE, Minami, M & Matsuda, H 1999, 'Clinical spectrum of congenital cystic disease of the lung in children', European Journal of Cardio-thoracic Surgery, vol. 15, no. 1, pp. 11-17. https://doi.org/10.1016/S1010-7940(98)00262-0
Takeda, Shin Ichi ; Miyoshi, Shinichiro ; Inoue, Masayoshi ; Omori, Ken Ichi ; Okumura, Meinoshin ; Yoon, Hyung Eun ; Minami, Masato ; Matsuda, Hikaru. / Clinical spectrum of congenital cystic disease of the lung in children. In: European Journal of Cardio-thoracic Surgery. 1999 ; Vol. 15, No. 1. pp. 11-17.
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