Clinical outcomes of Kyocera Modular Limb Salvage system after resection of bone sarcoma of the distal part of the femur: The Japanese Musculoskeletal Oncology Group study

Tomoki Nakamura, Akihiko Matsumine, Atsumasa Uchida, Akira Kawai, Yoshihiro Nishida, Toshiyuki Kunisada, Nobuhito Araki, Hideshi Sugiura, Masato Tomita, Masahiro Yokouchi, Takafumi Ueda, Akihiro Sudo

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Purpose: The Japanese Musculoskeletal Oncology Group have developed an original prosthesis called the Kyocera Modular Limb Salvage system (KMLS system). This prosthesis has a semi-rotating hinge joint and is particularly designed for people with an Asian body type. The metallic parts of the prosthesis are made entirely of titanium alloy. The purpose of this study is to evaluate the clinical outcomes of treatment using this system following tumour resection of primary bone sarcoma of the distal femur. Methods: Between 2002 and 2010, 82 patients with primary bone sarcomas of the distal femur were treated. Seventeen patients underwent stem cementation, while 65 patients were treated with cementless prostheses. The mean follow-up period after surgery was 61 months. Results: Complications were observed in 28 of the 82 patients. Forty-one complications occurred in these 28 patients. Thirteen prostheses (16 %) required revision surgery due to complications, including five cases of stem breakage, three deep infections, three cases of aseptic loosening, one case of displacement of the shaft cap and one case of breakage of the tibial tray. The five-year overall prosthetic survival rate was 80.0 %. Four of the 82 patients underwent subsequent amputation due to local recurrence. The five-year limb salvage rate was 94.5 %. The mean function score according to the scoring system of the Musculoskeletal Tumour Society was 21.8 points (72.5 %). Conclusions: Although further follow-up is required to determine the performance, this prosthesis is considered to be satisfactory for reconstruction of the distal femur after resection of bone sarcoma.

Original languageEnglish
Pages (from-to)825-830
Number of pages6
JournalInternational Orthopaedics
Issue number4
Publication statusPublished - Apr 2014



  • Bone sarcoma
  • Distal femur
  • Prosthesis

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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