Clinical outcomes of endoscopic mucosal resection and endoscopic submucosal dissection as a transoral treatment for superficial pharyngeal cancer

Noboru Hanaoka, Ryu Ishihara, Yoji Takeuchi, Motoyuki Suzuki, Hirokazu Uemura, Takashi Fujii, Kunitoshi Yoshino, Noriya Uedo, Koji Higashino, Takashi Ohta, Hiromitsu Kanzaki, Masao Hanafusa, Kengo Nagai, Fumi Matsui, Hiroyasu Iishi, Masaharu Tatsuta, Yasuhiko Tomita

Research output: Contribution to journalArticle

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Abstract

Background Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) have been introduced for the treatment of superficial pharyngeal cancer. Methods Sixty superficial pharyngeal cancers in 45 patients were treated by EMR or ESD. Resectability and curability, complications, and survival were analyzed retrospectively. Results The en bloc resection and curative resection rate were higher with ESD (100; 81.6%) than with EMR (59; 50%). In subgroup analysis with regard to tumor size ≤10 mm, both resection rates were comparative. All the patients had preserved larynx and swallowing, speech, and airway function. Two of the 45 patients died of other diseases, local recurrence was observed in 4 of 18 patients with noncurative resection with a median observation period of 38 months. No recurrence was observed in patients with curative resection. Conclusions ESD or EMR for superficial pharyngeal cancer is minimally invasive treatment and lesions larger than 10 mm should be referred for ESD.

Original languageEnglish
Pages (from-to)1248-1254
Number of pages7
JournalHead and Neck
Volume35
Issue number9
DOIs
Publication statusPublished - Sep 2013
Externally publishedYes

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Pharyngeal Neoplasms
Therapeutics
Endoscopic Mucosal Resection
Recurrence
Deglutition
Larynx
Observation

Keywords

  • endoscopic mucosal resection
  • endoscopic submucosal dissection
  • hypopharyngeal cancer
  • oropharyngeal cancer
  • superficial pharyngeal cancer

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Clinical outcomes of endoscopic mucosal resection and endoscopic submucosal dissection as a transoral treatment for superficial pharyngeal cancer. / Hanaoka, Noboru; Ishihara, Ryu; Takeuchi, Yoji; Suzuki, Motoyuki; Uemura, Hirokazu; Fujii, Takashi; Yoshino, Kunitoshi; Uedo, Noriya; Higashino, Koji; Ohta, Takashi; Kanzaki, Hiromitsu; Hanafusa, Masao; Nagai, Kengo; Matsui, Fumi; Iishi, Hiroyasu; Tatsuta, Masaharu; Tomita, Yasuhiko.

In: Head and Neck, Vol. 35, No. 9, 09.2013, p. 1248-1254.

Research output: Contribution to journalArticle

Hanaoka, N, Ishihara, R, Takeuchi, Y, Suzuki, M, Uemura, H, Fujii, T, Yoshino, K, Uedo, N, Higashino, K, Ohta, T, Kanzaki, H, Hanafusa, M, Nagai, K, Matsui, F, Iishi, H, Tatsuta, M & Tomita, Y 2013, 'Clinical outcomes of endoscopic mucosal resection and endoscopic submucosal dissection as a transoral treatment for superficial pharyngeal cancer', Head and Neck, vol. 35, no. 9, pp. 1248-1254. https://doi.org/10.1002/hed.23106
Hanaoka, Noboru ; Ishihara, Ryu ; Takeuchi, Yoji ; Suzuki, Motoyuki ; Uemura, Hirokazu ; Fujii, Takashi ; Yoshino, Kunitoshi ; Uedo, Noriya ; Higashino, Koji ; Ohta, Takashi ; Kanzaki, Hiromitsu ; Hanafusa, Masao ; Nagai, Kengo ; Matsui, Fumi ; Iishi, Hiroyasu ; Tatsuta, Masaharu ; Tomita, Yasuhiko. / Clinical outcomes of endoscopic mucosal resection and endoscopic submucosal dissection as a transoral treatment for superficial pharyngeal cancer. In: Head and Neck. 2013 ; Vol. 35, No. 9. pp. 1248-1254.
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