Clinical outcome of the Fontan operation in patients with impaired ventricular function

Yasuhiro Kotani, Shingo Kasahara, Yasuhiro Fujii, Ko Yoshizumi, Yu Oshima, Shin-ichi Ohtsuki, Teiji Akagi, Shunji Sano

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Objective: Although a staged Fontan strategy allows for an excellent outcome in high-risk patients, an impaired ventricular function remains a significant factor of early/late mortality and morbidity. This study evaluated the clinical outcome of the Fontan operation in patients with impaired ventricular function. Methods: A retrospective review was performed on 217 patients who had undergone the Fontan operation between 1991 and 2007. Results: Twenty-nine (13%) of the 217 patients had an impaired ventricular function (ejection fraction (EF) 2) was 82 ± 5%. The pulmonary artery pressure and pulmonary artery index were 11 ± 3 mmHg and 296 ± 102 mm2 m-2, respectively. All 29 patients underwent the Fontan operation without any early mortality. There were two late mortalities and two re-operations. EF was maintained at 59 ± 15% at a median follow-up of 7.5 (range: 1-19) years. The percent normal systemic ventricular end-diastolic volume decreased from 174 ± 95% to 124 ± 39% (p <0.05). The SpO2 increased to 92 ± 2%. The mean cardiothoracic ratio in chest X-ray and B-type natriuretic peptide were 51% (range: 35-68%) and 22 pg ml-1 (range: 9-382 pg ml-1), respectively. Three patients developed congestive heart failure, seven had arrhythmia and two developed protein-losing enteropathy. The New York Heart Association (NYHA) class functional class is I in 21 patients, II in five and III in one. Conclusions: Acceptable clinical outcomes were observed at an intermediate follow-up of the Fontan operation in patients with an impaired ventricular function.

Original languageEnglish
Pages (from-to)683-687
Number of pages5
JournalEuropean Journal of Cardio-thoracic Surgery
Volume36
Issue number4
DOIs
Publication statusPublished - Oct 2009

Fingerprint

Fontan Procedure
Ventricular Function
Stroke Volume
Pulmonary Artery
Mortality
Protein-Losing Enteropathies
Brain Natriuretic Peptide
Cardiac Arrhythmias
Thorax
Heart Failure
X-Rays
Morbidity
Pressure

Keywords

  • Clinical outcome
  • Fontan operation
  • Single ventricle
  • Ventricular function

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine

Cite this

Clinical outcome of the Fontan operation in patients with impaired ventricular function. / Kotani, Yasuhiro; Kasahara, Shingo; Fujii, Yasuhiro; Yoshizumi, Ko; Oshima, Yu; Ohtsuki, Shin-ichi; Akagi, Teiji; Sano, Shunji.

In: European Journal of Cardio-thoracic Surgery, Vol. 36, No. 4, 10.2009, p. 683-687.

Research output: Contribution to journalArticle

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