Clinical investigation of bronchioloalveolar carcinoma: A retrospective analysis of 53 patients in a single institution

Nobukazu Fujimoto, Yoshihiko Segawa, Nagio Takigawa, Katsuyuki Hotta, Daizo Kishino, Michihide Shimono, Masao Nakata, Hideyuki Saeki, Koichi Mandai, Kenji Eguch

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background. Bronchioloalveolar carcinoma (BAC) has been reported to have unique clinicopathological features. Patients and Methods. This retrospective study was performed using data base including 871 patients treated for primary lung cancer between 1981 and 1995. Results; The patients with BAC included a larger proportion of female (P = 0.029) and smoked less (P = 0.002) than those with non-BAC. There was no difference in survival between surgically resected patients with BAC and those with non-BAC. Clinical Stage IV patients with BAC had a better response to chemotherapy than did those with non-BAC. Survival in the former group was better than that in the latter on univariate analysis, but the significance of this difference was not confirmed multivariate analysis. Conclusion; The patients with BAC included a larger proportion of females and smoked less than those with non-BAC. Treatment results for BAC was comparable to those for non-BAC.

Original languageEnglish
Pages (from-to)1369-1373
Number of pages5
JournalAnticancer research
Volume19
Issue number2 B
Publication statusPublished - Jun 14 1999
Externally publishedYes

Keywords

  • Adenocarcinoma of the lung
  • Bronchioloalveolar carcinoma
  • Chemosensitivity
  • Surgical resection

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Fujimoto, N., Segawa, Y., Takigawa, N., Hotta, K., Kishino, D., Shimono, M., Nakata, M., Saeki, H., Mandai, K., & Eguch, K. (1999). Clinical investigation of bronchioloalveolar carcinoma: A retrospective analysis of 53 patients in a single institution. Anticancer research, 19(2 B), 1369-1373.