Clinical investigation of bronchioloalveolar carcinoma

A retrospective analysis of 53 patients in a single institution

Nobukazu Fujimoto, Yoshihiko Segawa, Nagio Takigawa, Katsuyuki Hotta, Daizo Kishino, Michihide Shimono, Masao Nakata, Hideyuki Saeki, Koichi Mandai, Kenji Eguch

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background. Bronchioloalveolar carcinoma (BAC) has been reported to have unique clinicopathological features. Patients and Methods. This retrospective study was performed using data base including 871 patients treated for primary lung cancer between 1981 and 1995. Results; The patients with BAC included a larger proportion of female (P = 0.029) and smoked less (P = 0.002) than those with non-BAC. There was no difference in survival between surgically resected patients with BAC and those with non-BAC. Clinical Stage IV patients with BAC had a better response to chemotherapy than did those with non-BAC. Survival in the former group was better than that in the latter on univariate analysis, but the significance of this difference was not confirmed multivariate analysis. Conclusion; The patients with BAC included a larger proportion of females and smoked less than those with non-BAC. Treatment results for BAC was comparable to those for non-BAC.

Original languageEnglish
Pages (from-to)1369-1373
Number of pages5
JournalAnticancer Research
Volume19
Issue number2 B
Publication statusPublished - 1999
Externally publishedYes

Fingerprint

Bronchiolo-Alveolar Adenocarcinoma
Carcinoma
Survival
Lung Neoplasms
Multivariate Analysis
Retrospective Studies
Databases
Drug Therapy

Keywords

  • Adenocarcinoma of the lung
  • Bronchioloalveolar carcinoma
  • Chemosensitivity
  • Surgical resection

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Fujimoto, N., Segawa, Y., Takigawa, N., Hotta, K., Kishino, D., Shimono, M., ... Eguch, K. (1999). Clinical investigation of bronchioloalveolar carcinoma: A retrospective analysis of 53 patients in a single institution. Anticancer Research, 19(2 B), 1369-1373.

Clinical investigation of bronchioloalveolar carcinoma : A retrospective analysis of 53 patients in a single institution. / Fujimoto, Nobukazu; Segawa, Yoshihiko; Takigawa, Nagio; Hotta, Katsuyuki; Kishino, Daizo; Shimono, Michihide; Nakata, Masao; Saeki, Hideyuki; Mandai, Koichi; Eguch, Kenji.

In: Anticancer Research, Vol. 19, No. 2 B, 1999, p. 1369-1373.

Research output: Contribution to journalArticle

Fujimoto, N, Segawa, Y, Takigawa, N, Hotta, K, Kishino, D, Shimono, M, Nakata, M, Saeki, H, Mandai, K & Eguch, K 1999, 'Clinical investigation of bronchioloalveolar carcinoma: A retrospective analysis of 53 patients in a single institution', Anticancer Research, vol. 19, no. 2 B, pp. 1369-1373.
Fujimoto, Nobukazu ; Segawa, Yoshihiko ; Takigawa, Nagio ; Hotta, Katsuyuki ; Kishino, Daizo ; Shimono, Michihide ; Nakata, Masao ; Saeki, Hideyuki ; Mandai, Koichi ; Eguch, Kenji. / Clinical investigation of bronchioloalveolar carcinoma : A retrospective analysis of 53 patients in a single institution. In: Anticancer Research. 1999 ; Vol. 19, No. 2 B. pp. 1369-1373.
@article{bdee68e71cb146408928a5884bde755d,
title = "Clinical investigation of bronchioloalveolar carcinoma: A retrospective analysis of 53 patients in a single institution",
abstract = "Background. Bronchioloalveolar carcinoma (BAC) has been reported to have unique clinicopathological features. Patients and Methods. This retrospective study was performed using data base including 871 patients treated for primary lung cancer between 1981 and 1995. Results; The patients with BAC included a larger proportion of female (P = 0.029) and smoked less (P = 0.002) than those with non-BAC. There was no difference in survival between surgically resected patients with BAC and those with non-BAC. Clinical Stage IV patients with BAC had a better response to chemotherapy than did those with non-BAC. Survival in the former group was better than that in the latter on univariate analysis, but the significance of this difference was not confirmed multivariate analysis. Conclusion; The patients with BAC included a larger proportion of females and smoked less than those with non-BAC. Treatment results for BAC was comparable to those for non-BAC.",
keywords = "Adenocarcinoma of the lung, Bronchioloalveolar carcinoma, Chemosensitivity, Surgical resection",
author = "Nobukazu Fujimoto and Yoshihiko Segawa and Nagio Takigawa and Katsuyuki Hotta and Daizo Kishino and Michihide Shimono and Masao Nakata and Hideyuki Saeki and Koichi Mandai and Kenji Eguch",
year = "1999",
language = "English",
volume = "19",
pages = "1369--1373",
journal = "Anticancer Research",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "2 B",

}

TY - JOUR

T1 - Clinical investigation of bronchioloalveolar carcinoma

T2 - A retrospective analysis of 53 patients in a single institution

AU - Fujimoto, Nobukazu

AU - Segawa, Yoshihiko

AU - Takigawa, Nagio

AU - Hotta, Katsuyuki

AU - Kishino, Daizo

AU - Shimono, Michihide

AU - Nakata, Masao

AU - Saeki, Hideyuki

AU - Mandai, Koichi

AU - Eguch, Kenji

PY - 1999

Y1 - 1999

N2 - Background. Bronchioloalveolar carcinoma (BAC) has been reported to have unique clinicopathological features. Patients and Methods. This retrospective study was performed using data base including 871 patients treated for primary lung cancer between 1981 and 1995. Results; The patients with BAC included a larger proportion of female (P = 0.029) and smoked less (P = 0.002) than those with non-BAC. There was no difference in survival between surgically resected patients with BAC and those with non-BAC. Clinical Stage IV patients with BAC had a better response to chemotherapy than did those with non-BAC. Survival in the former group was better than that in the latter on univariate analysis, but the significance of this difference was not confirmed multivariate analysis. Conclusion; The patients with BAC included a larger proportion of females and smoked less than those with non-BAC. Treatment results for BAC was comparable to those for non-BAC.

AB - Background. Bronchioloalveolar carcinoma (BAC) has been reported to have unique clinicopathological features. Patients and Methods. This retrospective study was performed using data base including 871 patients treated for primary lung cancer between 1981 and 1995. Results; The patients with BAC included a larger proportion of female (P = 0.029) and smoked less (P = 0.002) than those with non-BAC. There was no difference in survival between surgically resected patients with BAC and those with non-BAC. Clinical Stage IV patients with BAC had a better response to chemotherapy than did those with non-BAC. Survival in the former group was better than that in the latter on univariate analysis, but the significance of this difference was not confirmed multivariate analysis. Conclusion; The patients with BAC included a larger proportion of females and smoked less than those with non-BAC. Treatment results for BAC was comparable to those for non-BAC.

KW - Adenocarcinoma of the lung

KW - Bronchioloalveolar carcinoma

KW - Chemosensitivity

KW - Surgical resection

UR - http://www.scopus.com/inward/record.url?scp=0032994008&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032994008&partnerID=8YFLogxK

M3 - Article

VL - 19

SP - 1369

EP - 1373

JO - Anticancer Research

JF - Anticancer Research

SN - 0250-7005

IS - 2 B

ER -