Abstract
Sarcopenia is a complex syndrome defined by progressive and generalized loss of skeletal muscle mass and strength. Although sarcopenia is mainly associated with aging, cancer is also one of its causes. Sarcopenia is now drawing attention as a poor prognostic factor in cancer. In patients with gastric cancer associated with eating disorders that often leads to loss of weight and muscle, sarcopenia is particularly important. Its definition and method of assessment, however, vary between studies, thus these need to be standardized. Nevertheless, emerging evidence suggests that sarcopenia contributes independently to postoperative complications and overall survival in gastric cancer. Interventions preventing sarcopenia with targeted nutrition and exercise are currently explored. This review aims to provide an understanding of sarcopenia, emphasizing its importance in the management of gastric cancer.
| Original language | English |
|---|---|
| Pages (from-to) | 2241-2249 |
| Number of pages | 9 |
| Journal | Anticancer research |
| Volume | 39 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 1 2019 |
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Keywords
- Chemotherapy
- Gastric cancer
- Intervention
- Review
- Sarcopenia
- Surgery
ASJC Scopus subject areas
- Oncology
- Cancer Research
Cite this
Clinical impact of sarcopenia on gastric cancer. / Kuwada, Kazuya; Kuroda, Shinji; Kikuchi, Satoru; Yoshida, Ryuichi; Nishizaki, Masahiko; Kagawa, Shunsuke; Fujiwara, Toshiyoshi.
In: Anticancer research, Vol. 39, No. 5, 01.05.2019, p. 2241-2249.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Clinical impact of sarcopenia on gastric cancer
AU - Kuwada, Kazuya
AU - Kuroda, Shinji
AU - Kikuchi, Satoru
AU - Yoshida, Ryuichi
AU - Nishizaki, Masahiko
AU - Kagawa, Shunsuke
AU - Fujiwara, Toshiyoshi
PY - 2019/5/1
Y1 - 2019/5/1
N2 - Sarcopenia is a complex syndrome defined by progressive and generalized loss of skeletal muscle mass and strength. Although sarcopenia is mainly associated with aging, cancer is also one of its causes. Sarcopenia is now drawing attention as a poor prognostic factor in cancer. In patients with gastric cancer associated with eating disorders that often leads to loss of weight and muscle, sarcopenia is particularly important. Its definition and method of assessment, however, vary between studies, thus these need to be standardized. Nevertheless, emerging evidence suggests that sarcopenia contributes independently to postoperative complications and overall survival in gastric cancer. Interventions preventing sarcopenia with targeted nutrition and exercise are currently explored. This review aims to provide an understanding of sarcopenia, emphasizing its importance in the management of gastric cancer.
AB - Sarcopenia is a complex syndrome defined by progressive and generalized loss of skeletal muscle mass and strength. Although sarcopenia is mainly associated with aging, cancer is also one of its causes. Sarcopenia is now drawing attention as a poor prognostic factor in cancer. In patients with gastric cancer associated with eating disorders that often leads to loss of weight and muscle, sarcopenia is particularly important. Its definition and method of assessment, however, vary between studies, thus these need to be standardized. Nevertheless, emerging evidence suggests that sarcopenia contributes independently to postoperative complications and overall survival in gastric cancer. Interventions preventing sarcopenia with targeted nutrition and exercise are currently explored. This review aims to provide an understanding of sarcopenia, emphasizing its importance in the management of gastric cancer.
KW - Chemotherapy
KW - Gastric cancer
KW - Intervention
KW - Review
KW - Sarcopenia
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=85066429023&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85066429023&partnerID=8YFLogxK
U2 - 10.21873/anticanres.13340
DO - 10.21873/anticanres.13340
M3 - Review article
C2 - 31092415
AN - SCOPUS:85066429023
VL - 39
SP - 2241
EP - 2249
JO - Anticancer Research
JF - Anticancer Research
SN - 0250-7005
IS - 5
ER -