Clinical evidence for polyol efficacy.

P. Milgrom, E. M. Söderling, S. Nelson, D. L. Chi, Y. Nakai

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Xylitol is a safe dental caries preventive when incorporated into chewing gum or confections used habitually. The goal of this paper is to identify and assess the work on xylitol and other polyols and dental caries since 2008. Xylitol is effective when used by the mother prenatally or after delivery to prevent mutans transmission and subsequent dental caries in the offspring. One new completed trial confirmed that children of mothers who used xylitol lozenges after delivery had less dental caries than a comparison group. A similar study confirmed that the use of xylitol gum by the mother either prevented or postponed MS transmission to the offspring. Xylitol use among schoolchildren delivered via a gummy bear confection reduced S. mutans levels, but a once per day use of xylitol-containing toothpaste did not. Randomized trials, with caries outcomes, assessing xylitol-containing lozenges in adults and xylitol-containing gummy bears in children will release results in the coming year. Other studies are ongoing but are not systematic and will fail to answer important questions about how xylitol, or other polyols, can address the global dental caries problem.

Original languageEnglish
Pages (from-to)112-116
Number of pages5
JournalAdvances in dental research
Volume24
Issue number2
Publication statusPublished - Sep 2012
Externally publishedYes

Fingerprint

Xylitol
Dental Caries
Candy
Mothers
polyol
Chewing Gum
Toothpastes
Gingiva

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Milgrom, P., Söderling, E. M., Nelson, S., Chi, D. L., & Nakai, Y. (2012). Clinical evidence for polyol efficacy. Advances in dental research, 24(2), 112-116.

Clinical evidence for polyol efficacy. / Milgrom, P.; Söderling, E. M.; Nelson, S.; Chi, D. L.; Nakai, Y.

In: Advances in dental research, Vol. 24, No. 2, 09.2012, p. 112-116.

Research output: Contribution to journalArticle

Milgrom, P, Söderling, EM, Nelson, S, Chi, DL & Nakai, Y 2012, 'Clinical evidence for polyol efficacy.', Advances in dental research, vol. 24, no. 2, pp. 112-116.
Milgrom P, Söderling EM, Nelson S, Chi DL, Nakai Y. Clinical evidence for polyol efficacy. Advances in dental research. 2012 Sep;24(2):112-116.
Milgrom, P. ; Söderling, E. M. ; Nelson, S. ; Chi, D. L. ; Nakai, Y. / Clinical evidence for polyol efficacy. In: Advances in dental research. 2012 ; Vol. 24, No. 2. pp. 112-116.
@article{0b6f0ba4d4f1476594ab01907b6aa810,
title = "Clinical evidence for polyol efficacy.",
abstract = "Xylitol is a safe dental caries preventive when incorporated into chewing gum or confections used habitually. The goal of this paper is to identify and assess the work on xylitol and other polyols and dental caries since 2008. Xylitol is effective when used by the mother prenatally or after delivery to prevent mutans transmission and subsequent dental caries in the offspring. One new completed trial confirmed that children of mothers who used xylitol lozenges after delivery had less dental caries than a comparison group. A similar study confirmed that the use of xylitol gum by the mother either prevented or postponed MS transmission to the offspring. Xylitol use among schoolchildren delivered via a gummy bear confection reduced S. mutans levels, but a once per day use of xylitol-containing toothpaste did not. Randomized trials, with caries outcomes, assessing xylitol-containing lozenges in adults and xylitol-containing gummy bears in children will release results in the coming year. Other studies are ongoing but are not systematic and will fail to answer important questions about how xylitol, or other polyols, can address the global dental caries problem.",
author = "P. Milgrom and S{\"o}derling, {E. M.} and S. Nelson and Chi, {D. L.} and Y. Nakai",
year = "2012",
month = "9",
language = "English",
volume = "24",
pages = "112--116",
journal = "Advances in dental research",
issn = "0895-9374",
publisher = "International Association for Dental Research",
number = "2",

}

TY - JOUR

T1 - Clinical evidence for polyol efficacy.

AU - Milgrom, P.

AU - Söderling, E. M.

AU - Nelson, S.

AU - Chi, D. L.

AU - Nakai, Y.

PY - 2012/9

Y1 - 2012/9

N2 - Xylitol is a safe dental caries preventive when incorporated into chewing gum or confections used habitually. The goal of this paper is to identify and assess the work on xylitol and other polyols and dental caries since 2008. Xylitol is effective when used by the mother prenatally or after delivery to prevent mutans transmission and subsequent dental caries in the offspring. One new completed trial confirmed that children of mothers who used xylitol lozenges after delivery had less dental caries than a comparison group. A similar study confirmed that the use of xylitol gum by the mother either prevented or postponed MS transmission to the offspring. Xylitol use among schoolchildren delivered via a gummy bear confection reduced S. mutans levels, but a once per day use of xylitol-containing toothpaste did not. Randomized trials, with caries outcomes, assessing xylitol-containing lozenges in adults and xylitol-containing gummy bears in children will release results in the coming year. Other studies are ongoing but are not systematic and will fail to answer important questions about how xylitol, or other polyols, can address the global dental caries problem.

AB - Xylitol is a safe dental caries preventive when incorporated into chewing gum or confections used habitually. The goal of this paper is to identify and assess the work on xylitol and other polyols and dental caries since 2008. Xylitol is effective when used by the mother prenatally or after delivery to prevent mutans transmission and subsequent dental caries in the offspring. One new completed trial confirmed that children of mothers who used xylitol lozenges after delivery had less dental caries than a comparison group. A similar study confirmed that the use of xylitol gum by the mother either prevented or postponed MS transmission to the offspring. Xylitol use among schoolchildren delivered via a gummy bear confection reduced S. mutans levels, but a once per day use of xylitol-containing toothpaste did not. Randomized trials, with caries outcomes, assessing xylitol-containing lozenges in adults and xylitol-containing gummy bears in children will release results in the coming year. Other studies are ongoing but are not systematic and will fail to answer important questions about how xylitol, or other polyols, can address the global dental caries problem.

UR - http://www.scopus.com/inward/record.url?scp=84865237262&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84865237262&partnerID=8YFLogxK

M3 - Article

C2 - 22899692

AN - SCOPUS:84865237262

VL - 24

SP - 112

EP - 116

JO - Advances in dental research

JF - Advances in dental research

SN - 0895-9374

IS - 2

ER -