Clinical evaluation of cefozopran in the field of surgery

T. Matuno, Y. Kamikawa, A. Gouchi, K. Okanobu, K. Crita

Research output: Contribution to journalArticlepeer-review


We studied the clinical efficacy of cefozopran (CZOP), a newly developed injectable cephalosporin with a broad antibacterial spectrum, in surgical infections. The clinical efficacy was determined in 8 cases: cholangitis (1), localized peritonitis (2), subdiaphragmatic abscess (1), intraabdominal infection (1) and postoperative wound infection (3). CZOP was administered by intravenous drip infusion at a dose of 0.5~1 g twice daily for 3~11 days. The clinical efficacy was good in 4 patients, fair in 2 and poor in 2, showing an overall efficacy rate of 4/8. No adverse drug reactions or abnormal laboratory changes were observed.

Original languageEnglish
Pages (from-to)656-658
Number of pages3
Issue numberSUPPL. 4
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Pharmacology


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