Clinical evaluation of cefozopran in the field of surgery

T. Matuno, Y. Kamikawa, A. Gouchi, K. Okanobu, K. Crita

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Abstract

We studied the clinical efficacy of cefozopran (CZOP), a newly developed injectable cephalosporin with a broad antibacterial spectrum, in surgical infections. The clinical efficacy was determined in 8 cases: cholangitis (1), localized peritonitis (2), subdiaphragmatic abscess (1), intraabdominal infection (1) and postoperative wound infection (3). CZOP was administered by intravenous drip infusion at a dose of 0.5~1 g twice daily for 3~11 days. The clinical efficacy was good in 4 patients, fair in 2 and poor in 2, showing an overall efficacy rate of 4/8. No adverse drug reactions or abnormal laboratory changes were observed.

Original languageEnglish
Pages (from-to)656-658
Number of pages3
JournalChemotherapy
Volume41
Issue numberSUPPL. 4
Publication statusPublished - 1993

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ASJC Scopus subject areas

  • Pharmacology

Cite this

Matuno, T., Kamikawa, Y., Gouchi, A., Okanobu, K., & Crita, K. (1993). Clinical evaluation of cefozopran in the field of surgery. Chemotherapy, 41(SUPPL. 4), 656-658.