Clinical course and function of contralateral kidney following radical nephrectomy for renal cell carcinoma

Naoki Akebi, Tomoyasu Tsushima, Yasutomo Nasu, Masatoshi Noda, Yoshiyuki Miyaji, Takanori Murakami, Takaaki Inoue, Hiroyuki Ohmori, Hiromi Kumon

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Between 1975 and 1991, 118 patients with renal cell carcinoma were admitted to Okayama University Hospital to undergo radical nephrectomy. We herein review these cases retrospectively to evaluate the postoperative clinical course and renal function of the contralateral kidney. Five of the 118 patients needed hemodialysis throughout the follow-up period; 2 had metastasis to the contralateral kidney, 1 had a renal pelvic tumour and 2 had contralateral renal insufficiency with chronic renal disease. The renal function of those patients whose creatinine clearance level was preoperatively above 50 ml/min, was preserved. However 3 of 5 patients with a preoperative level below 50 ml/min, and proteinuria tended to have elevated plasma creatinine levels after surgery. Our study suggests that nephron- sparing surgery is needed for patients with limited renal function.

    Original languageEnglish
    Pages (from-to)649-652
    Number of pages4
    JournalNishinihon Journal of Urology
    Volume60
    Issue number9
    Publication statusPublished - Sep 1998

    Keywords

    • Clinical course
    • Contralateral kidney
    • Renal cell carcinoma
    • Renal function

    ASJC Scopus subject areas

    • Urology

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