Clinical and angiographic characteristics of retinal manifestations in cat scratch disease

Toshihiko Matsuo, Akihiro Yamaoka, Fumio Shiraga, Ippei Takasu, Toshio Okanouchi, Mikio Nagayama, Tetsuya Baba, Mizue Hayashi, Katsuhisa Sarada

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Purpose: To elucidate clinical and angiographic features of retinal manifestations in cat scratch disease. Methods: Clinical characteristics as well as fluorescein and indocyanine green (ICG) angiographic features were reviewed in 4 consecutive patients with retinal manifestations caused by serologically confirmed cat scratch disease. Results: A subretinal to intraretinal granuloma at the upper margin of the optic disc was found in 3 patients, while 1 patient developed subretinal to intraretinal granuloma in the midperiphery with serous retinal detachment. Fluorescein angiography revealed the abnormal vascular network of the peripapillary granuloma in the early phase followed by its dye leakage toward the late phase. Indocyanine green angiography demonstrated more clearly the abnormal vascular network with its minimal dye leakage than did fluorescein angiography. In contrast, only the late dye leakage was noted from granuloma of the midperipheral fundus by fluorescein angiography in one patient. Indocyanine green angiography detected no choroidal lesions other than the retinal lesions delineated by fluorescein angiography. The granulomas disappeared in response to a 4-week course of sulfamethoxazole-trimethoprim combined with steroids. Conclusions: Granuloma with abnormal vascular network as revealed by fluorescein and ICG angiography is characteristic of retinal manifestations in cat scratch disease. Copyright (C) 2000 Japanese Ophthalmological Society.

Original languageEnglish
Pages (from-to)182-186
Number of pages5
JournalJapanese Journal of Ophthalmology
Volume44
Issue number2
DOIs
Publication statusPublished - Mar 2000

Fingerprint

Cat-Scratch Disease
Granuloma
Indocyanine Green
Fluorescein Angiography
Blood Vessels
Angiography
Coloring Agents
Fluorescein
Optic Disk
Sulfamethoxazole Drug Combination Trimethoprim
Retinal Detachment
Steroids

Keywords

  • Angiomatosis
  • Cat scratch disease
  • Fluorescein angiography
  • Indocyanine green angiography

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Clinical and angiographic characteristics of retinal manifestations in cat scratch disease. / Matsuo, Toshihiko; Yamaoka, Akihiro; Shiraga, Fumio; Takasu, Ippei; Okanouchi, Toshio; Nagayama, Mikio; Baba, Tetsuya; Hayashi, Mizue; Sarada, Katsuhisa.

In: Japanese Journal of Ophthalmology, Vol. 44, No. 2, 03.2000, p. 182-186.

Research output: Contribution to journalArticle

Matsuo, Toshihiko ; Yamaoka, Akihiro ; Shiraga, Fumio ; Takasu, Ippei ; Okanouchi, Toshio ; Nagayama, Mikio ; Baba, Tetsuya ; Hayashi, Mizue ; Sarada, Katsuhisa. / Clinical and angiographic characteristics of retinal manifestations in cat scratch disease. In: Japanese Journal of Ophthalmology. 2000 ; Vol. 44, No. 2. pp. 182-186.
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