Circadian light-input pathways in Drosophila

Taishi Yoshii, Christiane Hermann-Luibl, Charlotte Helfrich-Föorster

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Light is the most important environmental cue to entrain the circadian clock in most animals. In the fruit fly Drosophila melanogaster, the light entrainment mechanisms of the clock have been wellstudied. The Drosophila brain contains approximately 150 neurons that rhythmically express circadian clock genes. These neurons are called “clock neurons” and control behavioral activity rhythms. Many clock neurons express the Cryptochrome (CRY) protein, which is sensitive to UV and blue light, and thus enables clock neurons deep in the brain to directly perceive light. In addition to the CRY protein, external photoreceptors in the Drosophila eyes play an important role in circadian light-input pathways. Recent studies have provided new insights into the mechanisms that integrate these light inputs into the circadian network of the brain. In this review, we will summarize the current knowledge on the light entrainment pathways in the Drosophila circadian clock.

Original languageEnglish
JournalCommunicative and Integrative Biology
Volume9
Issue number1
DOIs
Publication statusPublished - 2016

Fingerprint

Drosophila
Light
neurons
Circadian Clocks
Neurons
Cryptochromes
circadian rhythm
brain
Brain
Ultraviolet Rays
blue light
fruit flies
Drosophila melanogaster
photoreceptors
Diptera
Cues
ultraviolet radiation
Fruit
proteins
eyes

Keywords

  • Circadian clock
  • Circadian rhythm
  • Cryptochrome
  • Drosophila melanogaster
  • Light entrainment
  • Photoreceptor
  • Pigmentdispersing factor

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Circadian light-input pathways in Drosophila. / Yoshii, Taishi; Hermann-Luibl, Christiane; Helfrich-Föorster, Charlotte.

In: Communicative and Integrative Biology, Vol. 9, No. 1, 2016.

Research output: Contribution to journalArticle

Yoshii, Taishi ; Hermann-Luibl, Christiane ; Helfrich-Föorster, Charlotte. / Circadian light-input pathways in Drosophila. In: Communicative and Integrative Biology. 2016 ; Vol. 9, No. 1.
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