Chronic sclerosing pyelitis with an increased number of IgG4-positive plasma cells

Naoto Kuroda, Shoichiro Nakamura, Katsushi Miyazaki, Kaori Inoue, Masahiko Ohara, Keiko Mizuno, Yasuharu Sato, Tadashi Yoshino

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

IgG4-related disease has been recently described. This disease occurs in various anatomic locations including pancreas, biliary tract, liver, retroperitoneum, kidney, breast, lung, thyroid gland, prostate, salivary gland, lacrimal gland, and lymph node. In this article, we report the first case of IgG4-related disease arising in the renal pelvis. A 49-year-old Japanese woman was found to show left hydronephrosis by a medical checkup. Histological examination of the renal pelvic tumor showed IgG4-related disease. Her postoperative serum IgG4 was elevated, and this was compatible with IgG4-related disease. Systemic examination showed swelling of major and minor salivary glands and the lacrimal glands, and biopsy of the minor salivary gland revealed the finding of IgG4-related disease. Finally, pathologists and clinicians should be aware of the possibility that the renal pelvis may be involved in IgG4-related systemic disease.

Original languageEnglish
Pages (from-to)236-238
Number of pages3
JournalMedical Molecular Morphology
Volume42
Issue number4
DOIs
Publication statusPublished - Dec 2009

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Keywords

  • IgG4-related disease
  • Renal pelvis
  • Salivary gland

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Molecular Biology

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