Chromosomal localization of a strain-specific p53-related sequence in rat (Rattus norvegicus).

Tetsuo Kunieda, E. Kobayashi, H. Ikadai, T. Imamichi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Strain-specific restriction fragments hybridizing to human p53 gene cDNA, which was detected in only particular strains of inbred rat were revealed by Southern blot hybridization of DNAs of various inbred rat strains. Chromosomal location of the strain-specific fragments was determined on rat chromosome 1 between Kal and Pkc loci by linkage analysis using microsatellite marker loci. The fragments were concluded to be a novel p53-related sequence which is present in particular rat strains and absent from the remaining strains.

Original languageEnglish
Pages (from-to)301-305
Number of pages5
JournalExperimental Animals
Volume44
Issue number4
Publication statusPublished - Oct 1995

Fingerprint

Inbred Strains Rats
Rattus norvegicus
Rats
Chromosomes, Human, Pair 1
p53 Genes
rats
Southern Blotting
Microsatellite Repeats
Complementary DNA
DNA
loci
Chromosomes
nucleic acid hybridization
Southern blotting
linkage (genetics)
Genes
microsatellite repeats
chromosomes

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Chromosomal localization of a strain-specific p53-related sequence in rat (Rattus norvegicus). / Kunieda, Tetsuo; Kobayashi, E.; Ikadai, H.; Imamichi, T.

In: Experimental Animals, Vol. 44, No. 4, 10.1995, p. 301-305.

Research output: Contribution to journalArticle

Kunieda, Tetsuo ; Kobayashi, E. ; Ikadai, H. ; Imamichi, T. / Chromosomal localization of a strain-specific p53-related sequence in rat (Rattus norvegicus). In: Experimental Animals. 1995 ; Vol. 44, No. 4. pp. 301-305.
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