Choroidopathy in patients with sarcoidosis observed by simultaneous indocyanine green and fluorescein angiography

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Purpose: To examine choroidopathy in patients with sarcoidosis. Methods: In a prospective clinical study, 10 consecutive patients (20 eyes) with sarcoidosis underwent simultaneous indocyanine green (ICG) and fluorescein angiography (FA) with a double detector of scanning laser ophthalmoscopy. Angiographic findings recorded on videotapes were evaluated, and the relation of ICG angiographic findings with systemic activity and the extent of retinal inflammation was analyzed. Results: Indocyanine green angiographic findings, not evident with fluorescein, were multiple lobular hypofluorescent spots in the posterior pole in 10 eyes of 5 patients, isolated hypofluorescent plaques in 2 eyes of I patient, hyperfluorescent spots in 3 eyes of 2 patients, and segmental choroidal vascular wall staining in 6 eyes of 4 patients. The multiple lobular hypofluorescent spots with ICG were observed at a significantly higher rate in eyes with extensive retinal vascular leakage of fluorescein than in eyes with minimal leakage (chi-square test, P = 0.0007). Conclusions: The patients with sarcoidosis showed choroidal abnormalities that could be revealed by ICG angiography, but not by funduscopy or FA. Simultaneous ICG and FA angiography may be useful for examining choroidal lesions in sarcoidosis.

Original languageEnglish
Pages (from-to)16-21
Number of pages6
JournalRetina
Volume20
Issue number1
Publication statusPublished - 2000

Fingerprint

Indocyanine Green
Fluorescein Angiography
Sarcoidosis
Fluorescein
Angiography
Ophthalmoscopy
Retinal Vessels
Videotape Recording
Chi-Square Distribution
Blood Vessels
Lasers
Prospective Studies
Staining and Labeling
Inflammation

Keywords

  • Choroidapathy
  • Fluorescein angiography
  • Indocyanine green angiography
  • Sarcoidis

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

Cite this

Choroidopathy in patients with sarcoidosis observed by simultaneous indocyanine green and fluorescein angiography. / Matsuo, Toshihiko; Itami, Masako; Shiraga, Fumio.

In: Retina, Vol. 20, No. 1, 2000, p. 16-21.

Research output: Contribution to journalArticle

@article{963390e3b5c6432eb425582f71c4e320,
title = "Choroidopathy in patients with sarcoidosis observed by simultaneous indocyanine green and fluorescein angiography",
abstract = "Purpose: To examine choroidopathy in patients with sarcoidosis. Methods: In a prospective clinical study, 10 consecutive patients (20 eyes) with sarcoidosis underwent simultaneous indocyanine green (ICG) and fluorescein angiography (FA) with a double detector of scanning laser ophthalmoscopy. Angiographic findings recorded on videotapes were evaluated, and the relation of ICG angiographic findings with systemic activity and the extent of retinal inflammation was analyzed. Results: Indocyanine green angiographic findings, not evident with fluorescein, were multiple lobular hypofluorescent spots in the posterior pole in 10 eyes of 5 patients, isolated hypofluorescent plaques in 2 eyes of I patient, hyperfluorescent spots in 3 eyes of 2 patients, and segmental choroidal vascular wall staining in 6 eyes of 4 patients. The multiple lobular hypofluorescent spots with ICG were observed at a significantly higher rate in eyes with extensive retinal vascular leakage of fluorescein than in eyes with minimal leakage (chi-square test, P = 0.0007). Conclusions: The patients with sarcoidosis showed choroidal abnormalities that could be revealed by ICG angiography, but not by funduscopy or FA. Simultaneous ICG and FA angiography may be useful for examining choroidal lesions in sarcoidosis.",
keywords = "Choroidapathy, Fluorescein angiography, Indocyanine green angiography, Sarcoidis",
author = "Toshihiko Matsuo and Masako Itami and Fumio Shiraga",
year = "2000",
language = "English",
volume = "20",
pages = "16--21",
journal = "Retina",
issn = "0275-004X",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Choroidopathy in patients with sarcoidosis observed by simultaneous indocyanine green and fluorescein angiography

AU - Matsuo, Toshihiko

AU - Itami, Masako

AU - Shiraga, Fumio

PY - 2000

Y1 - 2000

N2 - Purpose: To examine choroidopathy in patients with sarcoidosis. Methods: In a prospective clinical study, 10 consecutive patients (20 eyes) with sarcoidosis underwent simultaneous indocyanine green (ICG) and fluorescein angiography (FA) with a double detector of scanning laser ophthalmoscopy. Angiographic findings recorded on videotapes were evaluated, and the relation of ICG angiographic findings with systemic activity and the extent of retinal inflammation was analyzed. Results: Indocyanine green angiographic findings, not evident with fluorescein, were multiple lobular hypofluorescent spots in the posterior pole in 10 eyes of 5 patients, isolated hypofluorescent plaques in 2 eyes of I patient, hyperfluorescent spots in 3 eyes of 2 patients, and segmental choroidal vascular wall staining in 6 eyes of 4 patients. The multiple lobular hypofluorescent spots with ICG were observed at a significantly higher rate in eyes with extensive retinal vascular leakage of fluorescein than in eyes with minimal leakage (chi-square test, P = 0.0007). Conclusions: The patients with sarcoidosis showed choroidal abnormalities that could be revealed by ICG angiography, but not by funduscopy or FA. Simultaneous ICG and FA angiography may be useful for examining choroidal lesions in sarcoidosis.

AB - Purpose: To examine choroidopathy in patients with sarcoidosis. Methods: In a prospective clinical study, 10 consecutive patients (20 eyes) with sarcoidosis underwent simultaneous indocyanine green (ICG) and fluorescein angiography (FA) with a double detector of scanning laser ophthalmoscopy. Angiographic findings recorded on videotapes were evaluated, and the relation of ICG angiographic findings with systemic activity and the extent of retinal inflammation was analyzed. Results: Indocyanine green angiographic findings, not evident with fluorescein, were multiple lobular hypofluorescent spots in the posterior pole in 10 eyes of 5 patients, isolated hypofluorescent plaques in 2 eyes of I patient, hyperfluorescent spots in 3 eyes of 2 patients, and segmental choroidal vascular wall staining in 6 eyes of 4 patients. The multiple lobular hypofluorescent spots with ICG were observed at a significantly higher rate in eyes with extensive retinal vascular leakage of fluorescein than in eyes with minimal leakage (chi-square test, P = 0.0007). Conclusions: The patients with sarcoidosis showed choroidal abnormalities that could be revealed by ICG angiography, but not by funduscopy or FA. Simultaneous ICG and FA angiography may be useful for examining choroidal lesions in sarcoidosis.

KW - Choroidapathy

KW - Fluorescein angiography

KW - Indocyanine green angiography

KW - Sarcoidis

UR - http://www.scopus.com/inward/record.url?scp=0034039596&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034039596&partnerID=8YFLogxK

M3 - Article

C2 - 10696741

AN - SCOPUS:0034039596

VL - 20

SP - 16

EP - 21

JO - Retina

JF - Retina

SN - 0275-004X

IS - 1

ER -