Choroidal lesions in sarcoidosis evaluated by indocyanine green angiography

We studied 21 eyes of 11 patients of systemic sarcoidosis by simultaneous fluorescein and indocyanine green (ICG) angiography using a scanning laser ophthalmoscope. We paid particular attention to choroidal abnormalities. ICG angiographic findings, which were not evident on fluorescein angiogram, included moth-eaten or patchy areas of hypofluorescence, hyperfluorescente dots, staining of choroidal vascular wall, and reduced number of choroidal vessels. The moth-eaten hypofluorescence was more frequent in eyes with extensive leakage of fluorescein from retinal vessels than in those with less leakage. These findings illustrate the value of simultaneous fluorescein and ICG angiography in assessing the choroidal lesions and in evaluating the activity of sarcoidosis in the choroid.