Abstract
Chemical modifications of the I287C mutant of a Burkholderia cepacia lipase afforded various I287C-X conjugates, among which I287C-PAA bearing an N-phenylacetamide (PAA) moiety showed excellent enantioselectivity and catalytic activity for secondary alcohols. Site-directed chemical modifications are powerful tools to control enantioselective biocatalysis.
Original language | English |
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Pages (from-to) | 1374-1376 |
Number of pages | 3 |
Journal | Chemistry Letters |
Volume | 44 |
Issue number | 10 |
DOIs | |
Publication status | Published - 2015 |
ASJC Scopus subject areas
- Chemistry(all)