Abstract
Hot springs are the most common infectious source of Legionella pneumophila in Japan. However, little is known about the association between L. pneumophila and environmental waters other than hot springs. In this study, water samples from 22 environmental water sites were surveyed; of the 22 samples, five were L. pneumophila positive (23%). L. pneumophila was mainly isolated from ashiyu foot spas, a type of hot spring for the feet (3/8, 38%). These isolates had genetic loci or genes that encoded the virulence factors of L. pneumophila. Moreover, these isolates showed higher intracellular growth and stronger cytotoxicity compared with the reference strain. These results suggest that ashiyu foot spa can be the original source for L. pneumophila infection.
| Original language | English |
|---|---|
| Article number | 514395 |
| Journal | BioMed Research International |
| Volume | 2013 |
| DOIs | |
| Publication status | Published - 2013 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Immunology and Microbiology(all)
- Medicine(all)
Cite this
Characterization of Legionella pneumophila isolated from environmental water and ashiyu foot spa. / Tachibana, Masato; Nakamoto, Masaya; Kimura, Yui; Shimizu, Takashi; Watarai, Masahisa.
In: BioMed Research International, Vol. 2013, 514395, 2013.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Characterization of Legionella pneumophila isolated from environmental water and ashiyu foot spa
AU - Tachibana, Masato
AU - Nakamoto, Masaya
AU - Kimura, Yui
AU - Shimizu, Takashi
AU - Watarai, Masahisa
PY - 2013
Y1 - 2013
N2 - Hot springs are the most common infectious source of Legionella pneumophila in Japan. However, little is known about the association between L. pneumophila and environmental waters other than hot springs. In this study, water samples from 22 environmental water sites were surveyed; of the 22 samples, five were L. pneumophila positive (23%). L. pneumophila was mainly isolated from ashiyu foot spas, a type of hot spring for the feet (3/8, 38%). These isolates had genetic loci or genes that encoded the virulence factors of L. pneumophila. Moreover, these isolates showed higher intracellular growth and stronger cytotoxicity compared with the reference strain. These results suggest that ashiyu foot spa can be the original source for L. pneumophila infection.
AB - Hot springs are the most common infectious source of Legionella pneumophila in Japan. However, little is known about the association between L. pneumophila and environmental waters other than hot springs. In this study, water samples from 22 environmental water sites were surveyed; of the 22 samples, five were L. pneumophila positive (23%). L. pneumophila was mainly isolated from ashiyu foot spas, a type of hot spring for the feet (3/8, 38%). These isolates had genetic loci or genes that encoded the virulence factors of L. pneumophila. Moreover, these isolates showed higher intracellular growth and stronger cytotoxicity compared with the reference strain. These results suggest that ashiyu foot spa can be the original source for L. pneumophila infection.
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UR - http://www.scopus.com/inward/citedby.url?scp=84880866944&partnerID=8YFLogxK
U2 - 10.1155/2013/514395
DO - 10.1155/2013/514395
M3 - Article
C2 - 23956987
AN - SCOPUS:84880866944
VL - 2013
JO - BioMed Research International
JF - BioMed Research International
SN - 2314-6133
M1 - 514395
ER -