Characterization of hollow fiber immobilized liposome membrane by using aqueous two-phase partitioning systems

Hiroyuki Sugaya, Hiroshi Umakoshi, Yuji Tohtake, Toshinori Shimanouchi, Ryoichi Kuboi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The modification of the surface of a polysulfone (PSf) membrane in a hollow fiber module was performed based on the evaluated hydrophobicity of the polymers used in its modification to develop a new type of membrane module immobilizing liposome. The surface net hydrophobicity of the polyvinylpyrrolidone (PVP), to be modified, was first characterized by using the aqueous two-phase partitioning method. The hollow fiber module using the PVP-modified PSf membrane was characterized based on the adsorption behaviors of standard amino acids, showing that the membrane surface was found to have a hydrophilic surface nearly equal to the difference in aqueous two-phase systems. The immobilized liposome membrane (ILM) in the above module was found to have a hydrophobic potential, thus promoting the adsorption of the hydrophobic molecules on its surface.

Original languageEnglish
Pages (from-to)103-109
Number of pages7
JournalSolvent Extraction Research and Development
Volume16
Publication statusPublished - Sep 7 2009
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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