Characterization of hollow fiber immobilized liposome membrane by using aqueous two-phase partitioning systems

The modification of the surface of a polysulfone (PSf) membrane in a hollow fiber module was performed based on the evaluated hydrophobicity of the polymers used in its modification to develop a new type of membrane module immobilizing liposome. The surface net hydrophobicity of the polyvinylpyrrolidone (PVP), to be modified, was first characterized by using the aqueous two-phase partitioning method. The hollow fiber module using the PVP-modified PSf membrane was characterized based on the adsorption behaviors of standard amino acids, showing that the membrane surface was found to have a hydrophilic surface nearly equal to the difference in aqueous two-phase systems. The immobilized liposome membrane (ILM) in the above module was found to have a hydrophobic potential, thus promoting the adsorption of the hydrophobic molecules on its surface.