Characteristics of bone morphogenetic protein-induced chondroid bone: Histochemical, immunohistochemical and in situ hybridization examinations

T. Kawakami; T. Kawai; A. Kimura; H. Hasegawa; H. Tsujigiwa; M. Gunduz; H. Nagatsuka; N. Nagai

doi:10.1177/147323000102900603

Characteristics of bone morphogenetic protein-induced chondroid bone: Histochemical, immunohistochemical and in situ hybridization examinations

T. Kawakami, T. Kawai, A. Kimura, H. Hasegawa, H. Tsujigiwa, M. Gunduz, H. Nagatsuka, N. Nagai

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The third ossification mode, known as transchondroid bone formation, is displayed chiefly in the bone morphogenetic protein (BMP)-induced heterotopic bone formation model. This paper describes the results of histopathological, histochemical, immunohistochemical, and in situ hybridization examinations of BMP-induced heterotopic bone in mice. The research focuses on the localization of typical matrix proteins (peptide and its mRNA) of cartilage and bone - type-I and type-II collagen, osteocalcin and osteopontin - in the chondroid bone matrix.

Original language	English
Pages (from-to)	480-487
Number of pages	8
Journal	Journal of International Medical Research
Volume	29
Issue number	6
DOIs	https://doi.org/10.1177/147323000102900603
Publication status	Published - 2001

Keywords

Bone matrix
Bone morphogenetic protein
Chondroid bone
Immunohistochemistry
In situ hybridization
MRNA
Ossification

ASJC Scopus subject areas

Biochemistry
Cell Biology
Biochemistry, medical

Access to Document

10.1177/147323000102900603

Fingerprint Dive into the research topics of 'Characteristics of bone morphogenetic protein-induced chondroid bone: Histochemical, immunohistochemical and in situ hybridization examinations'. Together they form a unique fingerprint.

Cite this

Characteristics of bone morphogenetic protein-induced chondroid bone : Histochemical, immunohistochemical and in situ hybridization examinations. / Kawakami, T.; Kawai, T.; Kimura, A.; Hasegawa, H.; Tsujigiwa, H.; Gunduz, M.; Nagatsuka, H.; Nagai, N.

In: Journal of International Medical Research, Vol. 29, No. 6, 2001, p. 480-487.

Research output: Contribution to journal › Article › peer-review

@article{c5ea76a392b447a2bc8e59a97f956a37,

title = "Characteristics of bone morphogenetic protein-induced chondroid bone: Histochemical, immunohistochemical and in situ hybridization examinations",

abstract = "The third ossification mode, known as transchondroid bone formation, is displayed chiefly in the bone morphogenetic protein (BMP)-induced heterotopic bone formation model. This paper describes the results of histopathological, histochemical, immunohistochemical, and in situ hybridization examinations of BMP-induced heterotopic bone in mice. The research focuses on the localization of typical matrix proteins (peptide and its mRNA) of cartilage and bone - type-I and type-II collagen, osteocalcin and osteopontin - in the chondroid bone matrix.",

keywords = "Bone matrix, Bone morphogenetic protein, Chondroid bone, Immunohistochemistry, In situ hybridization, MRNA, Ossification",

author = "T. Kawakami and T. Kawai and A. Kimura and H. Hasegawa and H. Tsujigiwa and M. Gunduz and H. Nagatsuka and N. Nagai",

year = "2001",

doi = "10.1177/147323000102900603",

language = "English",

volume = "29",

pages = "480--487",

journal = "Journal of International Medical Research",

issn = "0300-0605",

publisher = "Field House Publishing LLP",

number = "6",

}

TY - JOUR

T1 - Characteristics of bone morphogenetic protein-induced chondroid bone

T2 - Histochemical, immunohistochemical and in situ hybridization examinations

AU - Kawakami, T.

AU - Kawai, T.

AU - Kimura, A.

AU - Hasegawa, H.

AU - Tsujigiwa, H.

AU - Gunduz, M.

AU - Nagatsuka, H.

AU - Nagai, N.

PY - 2001

Y1 - 2001

N2 - The third ossification mode, known as transchondroid bone formation, is displayed chiefly in the bone morphogenetic protein (BMP)-induced heterotopic bone formation model. This paper describes the results of histopathological, histochemical, immunohistochemical, and in situ hybridization examinations of BMP-induced heterotopic bone in mice. The research focuses on the localization of typical matrix proteins (peptide and its mRNA) of cartilage and bone - type-I and type-II collagen, osteocalcin and osteopontin - in the chondroid bone matrix.

AB - The third ossification mode, known as transchondroid bone formation, is displayed chiefly in the bone morphogenetic protein (BMP)-induced heterotopic bone formation model. This paper describes the results of histopathological, histochemical, immunohistochemical, and in situ hybridization examinations of BMP-induced heterotopic bone in mice. The research focuses on the localization of typical matrix proteins (peptide and its mRNA) of cartilage and bone - type-I and type-II collagen, osteocalcin and osteopontin - in the chondroid bone matrix.

KW - Bone matrix

KW - Bone morphogenetic protein

KW - Chondroid bone

KW - Immunohistochemistry

KW - In situ hybridization

KW - MRNA

KW - Ossification

UR - http://www.scopus.com/inward/record.url?scp=0035670510&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035670510&partnerID=8YFLogxK

U2 - 10.1177/147323000102900603

DO - 10.1177/147323000102900603

M3 - Article

C2 - 11803731

AN - SCOPUS:0035670510

VL - 29

SP - 480

EP - 487

JO - Journal of International Medical Research

JF - Journal of International Medical Research

SN - 0300-0605

IS - 6

ER -