TY - JOUR
T1 - Characteristics of bone morphogenetic protein-induced chondroid bone
T2 - Histochemical, immunohistochemical and in situ hybridization examinations
AU - Kawakami, T.
AU - Kawai, T.
AU - Kimura, A.
AU - Hasegawa, H.
AU - Tsujigiwa, H.
AU - Gunduz, M.
AU - Nagatsuka, H.
AU - Nagai, N.
PY - 2001
Y1 - 2001
N2 - The third ossification mode, known as transchondroid bone formation, is displayed chiefly in the bone morphogenetic protein (BMP)-induced heterotopic bone formation model. This paper describes the results of histopathological, histochemical, immunohistochemical, and in situ hybridization examinations of BMP-induced heterotopic bone in mice. The research focuses on the localization of typical matrix proteins (peptide and its mRNA) of cartilage and bone - type-I and type-II collagen, osteocalcin and osteopontin - in the chondroid bone matrix.
AB - The third ossification mode, known as transchondroid bone formation, is displayed chiefly in the bone morphogenetic protein (BMP)-induced heterotopic bone formation model. This paper describes the results of histopathological, histochemical, immunohistochemical, and in situ hybridization examinations of BMP-induced heterotopic bone in mice. The research focuses on the localization of typical matrix proteins (peptide and its mRNA) of cartilage and bone - type-I and type-II collagen, osteocalcin and osteopontin - in the chondroid bone matrix.
KW - Bone matrix
KW - Bone morphogenetic protein
KW - Chondroid bone
KW - Immunohistochemistry
KW - In situ hybridization
KW - MRNA
KW - Ossification
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U2 - 10.1177/147323000102900603
DO - 10.1177/147323000102900603
M3 - Article
C2 - 11803731
AN - SCOPUS:0035670510
VL - 29
SP - 480
EP - 487
JO - Journal of International Medical Research
JF - Journal of International Medical Research
SN - 0300-0605
IS - 6
ER -