Characteristics of audiogram configuration in multiple-system atrophy C and cortical cerebellar atrophy

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Conclusion: The prevalence of low-tone hearing loss (LTHL) is significantly high in spinocerebellar degeneration (SCD) with cerebellar predominance, including multiple-system atrophy C (MSA-C) and cortical cerebellar atrophy (CCA). Objective: This study aimed to test the hypothesis that SCD with cerebellar predominance, MSA-C and CCA may cause auditory symptoms. Methods: The shape and threshold of pure-tone audiograms were evaluated for MSA-C (n = 47; mean (± SD) age, 61.6 ± 8.9 years), CCA (n = 16; 62.8 ± 9.5 years), and age-matched controls (n = 169; 62.5 ± 10.7 years). To differentiate specific hearing loss for MSA-C and CCA from presbycusis, the shape of audiograms was examined based on previously established audiological criteria. Results: When audiogram shape was defined according to audiological criteria, the odds ratio for LTHL in SCD compared to controls was 2.492 (95% confidence interval (CI) = 1.208-5.139; p < 0.05, Pearsons Chi-square test) in MSA-C and 2.194 (95% CI = 0.709-6.795) in CCA. When the selection of audiogram shape according to these criteria was verified by three certified audiologists, odds ratios for LTHL in MSA-C and CCA were 3.243 (95% CI = 1.320-7.969) and 3.692 (95% CI = 1.052-12.957), respectively, significantly higher than in controls.

Original languageEnglish
Pages (from-to)266-270
Number of pages5
JournalActa Oto-Laryngologica
Volume136
Issue number3
DOIs
Publication statusPublished - Mar 3 2016

Keywords

  • Audiogram configuration
  • Cortical cerebellar atrophy
  • Low-tone hearing loss
  • Multiple-system atrophy C
  • Sensorineural hearing loss
  • Spinocerebellar degeneration

ASJC Scopus subject areas

  • Otorhinolaryngology

Fingerprint Dive into the research topics of 'Characteristics of audiogram configuration in multiple-system atrophy C and cortical cerebellar atrophy'. Together they form a unique fingerprint.

  • Cite this