Characteristics of a novel Pseudomonas aeruginosa bacteriophage, PAJU2, which is genetically related to bacteriophage D3

Jumpei Uchiyama, Mohammad Rashel, Tetsuya Matsumoto, Yoshinobu Sumiyama, Hiroshi Wakiguchi, Shigenobu Matsuzaki

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

Pseudomonas aeruginosa bacteriophage (phage) is one of the most taxonomically and genetically diverse phages. Although phage D3 is one of well-studied P. aeruginosa phages, no D3-related P. aeruginosa phage has been reported. We report a novel P. aeruginosa siphovirus, PAJU2, which is genetically related to but morphology distinct (highly elongated head) from phage D3. A PAJU2 capsid protein, Orf3, is thought to be synthesized as a protein fused to a prohead protease and is autocatalytically cleaved, which may form the head chain mail. Despite such morphological differences, PAJU2 is expected to be a useful genetic reference for phage D3.

Original languageEnglish
Pages (from-to)131-134
Number of pages4
JournalVirus research
Volume139
Issue number1
DOIs
Publication statusPublished - Jan 2009
Externally publishedYes

Keywords

  • Bacteriophage
  • Genome
  • Pseudomonas aeruginosa

ASJC Scopus subject areas

  • Cancer Research
  • Virology
  • Infectious Diseases

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