Changes of SOD-like Substances in Mouse Organs after Low-dose X-ray Irradiation

Kiyonori Yamaoka, Shuji Kojima, Takahara Nomura

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

We demonstrated that low-dose irradiation with 50 cGy of X-ray induces in vivo production of superoxide dismutase (SOD)-like substances and accelerates antioxidant activity. To elucidate the defense mechanism against X-ray radiation, we examined which components among these SOD-like substances, such as SOD, vitamin C and celuroplasmin, are produced by low-dose irradiation. Our study revealed that SOD-like specific activity hardly involved SOD-like substances other than SOD. Moreover, it is suggested that low-dose irradiation induced synthesis and production of SOD itself, leading to elevation of SOD-specific activity.

Original languageEnglish
Pages (from-to)23-28
Number of pages6
JournalPhysiological chemistry and physics and medical NMR
Volume31
Issue number1
Publication statusPublished - Dec 1 1999

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Physiology
  • Spectroscopy

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