Changes of SOD-like Substances in Mouse Organs after Low-dose X-ray Irradiation

Kiyonori Yamaoka, Shuji Kojima, Takahara Nomura

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

We demonstrated that low-dose irradiation with 50 cGy of X-ray induces in vivo production of superoxide dismutase (SOD)-like substances and accelerates antioxidant activity. To elucidate the defense mechanism against X-ray radiation, we examined which components among these SOD-like substances, such as SOD, vitamin C and celuroplasmin, are produced by low-dose irradiation. Our study revealed that SOD-like specific activity hardly involved SOD-like substances other than SOD. Moreover, it is suggested that low-dose irradiation induced synthesis and production of SOD itself, leading to elevation of SOD-specific activity.

Original languageEnglish
Pages (from-to)23-28
Number of pages6
JournalPhysiological Chemistry and Physics and Medical NMR
Volume31
Issue number1
Publication statusPublished - 1999

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Superoxide Dismutase
Dosimetry
X-Rays
Irradiation
X rays
Ascorbic Acid
Antioxidants
Radiation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Biophysics
  • Physiology
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Changes of SOD-like Substances in Mouse Organs after Low-dose X-ray Irradiation. / Yamaoka, Kiyonori; Kojima, Shuji; Nomura, Takahara.

In: Physiological Chemistry and Physics and Medical NMR, Vol. 31, No. 1, 1999, p. 23-28.

Research output: Contribution to journalArticle

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