Change of concentrations of trace elements and protein contents in the liver of zinc deficient mice

R. Minayoshi, T. Ohyama, N. Kinugawa, J. Kamishima, T. Ogi, K. Ishikawa, M. Noguchi, H. Suganuma, K. Takahashi, S. Enomoto, M. Yanaga

Research output: Contribution to journalArticlepeer-review

Abstract

The concentrations of essential trace elements and proteins in cytosolic fraction of hepatic cells of mice fed with Zn-deficient diet (Zn-def, mice) and control were determined by ICP-MS and BCA protein assay method, respectively, after division into forty fractions by gel filtration chromatography. The concentrations of zinc and proteins decreased in the 14-17th fractions of Zn-def, mice, whereas cobalt concentrations increased in the 14, 17, and 18th fractions. However, no significant differences were found on the gel after SDS-PAGE for the 12-21st fractions, although the BCA protein assay date showed the decrease of protein amounts in 13-15th fractions of Zn-def. mice.

Original languageEnglish
Pages (from-to)429-431
Number of pages3
JournalJournal of Radioanalytical and Nuclear Chemistry
Volume272
Issue number2
DOIs
Publication statusPublished - May 1 2007

ASJC Scopus subject areas

  • Analytical Chemistry
  • Nuclear Energy and Engineering
  • Radiology Nuclear Medicine and imaging
  • Pollution
  • Spectroscopy
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

Fingerprint Dive into the research topics of 'Change of concentrations of trace elements and protein contents in the liver of zinc deficient mice'. Together they form a unique fingerprint.

Cite this