Abstract
To determine the efficacy of flow-sensitive alternating inversion recovery using half-Fourier single-shot turbo spin-echo (FAIR-HASTE) in detecting cerebral hypoperfusion in chronic carotid occlusive disease, we subjected 12 patients with various degrees of cervical internal carotid artery stenoses and/or occlusion (Stenosis group) and 24 volunteers (Normal group) to FAIR-HASTE. In addition, 10 out of 12 patients in the Stenosis group underwent dynamic susceptibility contrast-perfusion magnetic resonance imaging (DSC-pMRI) before and after revascularization in the dominantly affected side. The absolute asymmetry indexes (Als) of both cerebral hemispheres in the Normal and Stenosis groups were compared in FAIR-HASTE. In addition, the Als were compared with those in the Stenosis group before and after revascularization in both FAIR-HASTE and regional cerebral blood flow (rCBF), calculated with DSC-pMRI. A statistically significant difference was recognized between the Als in the Normal and Stenosis groups (AI = 2.25 ± 1.92, 8.09 ± 4.60, respectively; p <0.0001). Furthermore, in the Stenosis group the Als on both FAIR-HASTE (8.88 ± 4.93, 2.22 ± 1.79, respectively; p = 0.0003) and rCBF (7.13 ± 3.57, 1.25 ± 1.33, respectively; p = 0.0003) significantly decreased after revascularization. In the Stenosis group, before revascularization, signal intensity on both FAIR-HASTE and rCBF had a tendency to be lower in the dominantly affected side. FAIR-HASTE imaging was useful in the detection and evaluation of cerebral hypoperfusion in chronic occlusive carotid disease.
| Original language | English |
|---|---|
| Pages (from-to) | 215-221 |
| Number of pages | 7 |
| Journal | Acta Medica Okayama |
| Volume | 60 |
| Issue number | 4 |
| Publication status | Published - 2006 |
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Keywords
- Brain
- FAIR
- HASTE
- MRI
- Perfusion
ASJC Scopus subject areas
- Medicine(all)
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Cerebral perfusion MR imaging using FAIR-HASTE in chronic carotid occlusive disease : Comparison with dynamic susceptibility contrast-perfusion MR imaging. / Ida, Kentaro; Akaki, Shiro; Sei, Tetsuro; Tsunoda, Masatoshi; Kanazawa, Susumu.
In: Acta Medica Okayama, Vol. 60, No. 4, 2006, p. 215-221.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cerebral perfusion MR imaging using FAIR-HASTE in chronic carotid occlusive disease
T2 - Comparison with dynamic susceptibility contrast-perfusion MR imaging
AU - Ida, Kentaro
AU - Akaki, Shiro
AU - Sei, Tetsuro
AU - Tsunoda, Masatoshi
AU - Kanazawa, Susumu
PY - 2006
Y1 - 2006
N2 - To determine the efficacy of flow-sensitive alternating inversion recovery using half-Fourier single-shot turbo spin-echo (FAIR-HASTE) in detecting cerebral hypoperfusion in chronic carotid occlusive disease, we subjected 12 patients with various degrees of cervical internal carotid artery stenoses and/or occlusion (Stenosis group) and 24 volunteers (Normal group) to FAIR-HASTE. In addition, 10 out of 12 patients in the Stenosis group underwent dynamic susceptibility contrast-perfusion magnetic resonance imaging (DSC-pMRI) before and after revascularization in the dominantly affected side. The absolute asymmetry indexes (Als) of both cerebral hemispheres in the Normal and Stenosis groups were compared in FAIR-HASTE. In addition, the Als were compared with those in the Stenosis group before and after revascularization in both FAIR-HASTE and regional cerebral blood flow (rCBF), calculated with DSC-pMRI. A statistically significant difference was recognized between the Als in the Normal and Stenosis groups (AI = 2.25 ± 1.92, 8.09 ± 4.60, respectively; p <0.0001). Furthermore, in the Stenosis group the Als on both FAIR-HASTE (8.88 ± 4.93, 2.22 ± 1.79, respectively; p = 0.0003) and rCBF (7.13 ± 3.57, 1.25 ± 1.33, respectively; p = 0.0003) significantly decreased after revascularization. In the Stenosis group, before revascularization, signal intensity on both FAIR-HASTE and rCBF had a tendency to be lower in the dominantly affected side. FAIR-HASTE imaging was useful in the detection and evaluation of cerebral hypoperfusion in chronic occlusive carotid disease.
AB - To determine the efficacy of flow-sensitive alternating inversion recovery using half-Fourier single-shot turbo spin-echo (FAIR-HASTE) in detecting cerebral hypoperfusion in chronic carotid occlusive disease, we subjected 12 patients with various degrees of cervical internal carotid artery stenoses and/or occlusion (Stenosis group) and 24 volunteers (Normal group) to FAIR-HASTE. In addition, 10 out of 12 patients in the Stenosis group underwent dynamic susceptibility contrast-perfusion magnetic resonance imaging (DSC-pMRI) before and after revascularization in the dominantly affected side. The absolute asymmetry indexes (Als) of both cerebral hemispheres in the Normal and Stenosis groups were compared in FAIR-HASTE. In addition, the Als were compared with those in the Stenosis group before and after revascularization in both FAIR-HASTE and regional cerebral blood flow (rCBF), calculated with DSC-pMRI. A statistically significant difference was recognized between the Als in the Normal and Stenosis groups (AI = 2.25 ± 1.92, 8.09 ± 4.60, respectively; p <0.0001). Furthermore, in the Stenosis group the Als on both FAIR-HASTE (8.88 ± 4.93, 2.22 ± 1.79, respectively; p = 0.0003) and rCBF (7.13 ± 3.57, 1.25 ± 1.33, respectively; p = 0.0003) significantly decreased after revascularization. In the Stenosis group, before revascularization, signal intensity on both FAIR-HASTE and rCBF had a tendency to be lower in the dominantly affected side. FAIR-HASTE imaging was useful in the detection and evaluation of cerebral hypoperfusion in chronic occlusive carotid disease.
KW - Brain
KW - FAIR
KW - HASTE
KW - MRI
KW - Perfusion
UR - http://www.scopus.com/inward/record.url?scp=33748445903&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33748445903&partnerID=8YFLogxK
M3 - Article
C2 - 16943858
AN - SCOPUS:33748445903
VL - 60
SP - 215
EP - 221
JO - Acta Medica Okayama
JF - Acta Medica Okayama
SN - 0386-300X
IS - 4
ER -