Cerebral perfusion MR imaging using FAIR-HASTE in chronic carotid occlusive disease: Comparison with dynamic susceptibility contrast-perfusion MR imaging

Kentaro Ida, Shiro Akaki, Tetsuro Sei, Masatoshi Tsunoda, Susumu Kanazawa

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

To determine the efficacy of flow-sensitive alternating inversion recovery using half-Fourier single-shot turbo spin-echo (FAIR-HASTE) in detecting cerebral hypoperfusion in chronic carotid occlusive disease, we subjected 12 patients with various degrees of cervical internal carotid artery stenoses and/or occlusion (Stenosis group) and 24 volunteers (Normal group) to FAIR-HASTE. In addition, 10 out of 12 patients in the Stenosis group underwent dynamic susceptibility contrast-perfusion magnetic resonance imaging (DSC-pMRI) before and after revascularization in the dominantly affected side. The absolute asymmetry indexes (Als) of both cerebral hemispheres in the Normal and Stenosis groups were compared in FAIR-HASTE. In addition, the Als were compared with those in the Stenosis group before and after revascularization in both FAIR-HASTE and regional cerebral blood flow (rCBF), calculated with DSC-pMRI. A statistically significant difference was recognized between the Als in the Normal and Stenosis groups (AI = 2.25 ± 1.92, 8.09 ± 4.60, respectively; p <0.0001). Furthermore, in the Stenosis group the Als on both FAIR-HASTE (8.88 ± 4.93, 2.22 ± 1.79, respectively; p = 0.0003) and rCBF (7.13 ± 3.57, 1.25 ± 1.33, respectively; p = 0.0003) significantly decreased after revascularization. In the Stenosis group, before revascularization, signal intensity on both FAIR-HASTE and rCBF had a tendency to be lower in the dominantly affected side. FAIR-HASTE imaging was useful in the detection and evaluation of cerebral hypoperfusion in chronic occlusive carotid disease.

Original languageEnglish
Pages (from-to)215-221
Number of pages7
JournalActa Medica Okayama
Volume60
Issue number4
Publication statusPublished - 2006

Fingerprint

Perfusion Imaging
Pathologic Constriction
Cerebrovascular Circulation
Imaging techniques
Recovery
Regional Blood Flow
Blood
Magnetic Resonance Angiography
Magnetic resonance
Carotid Stenosis
Cerebrum
Healthy Volunteers
Magnetic Resonance Imaging

Keywords

  • Brain
  • FAIR
  • HASTE
  • MRI
  • Perfusion

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Cerebral perfusion MR imaging using FAIR-HASTE in chronic carotid occlusive disease : Comparison with dynamic susceptibility contrast-perfusion MR imaging. / Ida, Kentaro; Akaki, Shiro; Sei, Tetsuro; Tsunoda, Masatoshi; Kanazawa, Susumu.

In: Acta Medica Okayama, Vol. 60, No. 4, 2006, p. 215-221.

Research output: Contribution to journalArticle

@article{f2ef9e6228f549088898b119a8a42ff5,
title = "Cerebral perfusion MR imaging using FAIR-HASTE in chronic carotid occlusive disease: Comparison with dynamic susceptibility contrast-perfusion MR imaging",
abstract = "To determine the efficacy of flow-sensitive alternating inversion recovery using half-Fourier single-shot turbo spin-echo (FAIR-HASTE) in detecting cerebral hypoperfusion in chronic carotid occlusive disease, we subjected 12 patients with various degrees of cervical internal carotid artery stenoses and/or occlusion (Stenosis group) and 24 volunteers (Normal group) to FAIR-HASTE. In addition, 10 out of 12 patients in the Stenosis group underwent dynamic susceptibility contrast-perfusion magnetic resonance imaging (DSC-pMRI) before and after revascularization in the dominantly affected side. The absolute asymmetry indexes (Als) of both cerebral hemispheres in the Normal and Stenosis groups were compared in FAIR-HASTE. In addition, the Als were compared with those in the Stenosis group before and after revascularization in both FAIR-HASTE and regional cerebral blood flow (rCBF), calculated with DSC-pMRI. A statistically significant difference was recognized between the Als in the Normal and Stenosis groups (AI = 2.25 ± 1.92, 8.09 ± 4.60, respectively; p <0.0001). Furthermore, in the Stenosis group the Als on both FAIR-HASTE (8.88 ± 4.93, 2.22 ± 1.79, respectively; p = 0.0003) and rCBF (7.13 ± 3.57, 1.25 ± 1.33, respectively; p = 0.0003) significantly decreased after revascularization. In the Stenosis group, before revascularization, signal intensity on both FAIR-HASTE and rCBF had a tendency to be lower in the dominantly affected side. FAIR-HASTE imaging was useful in the detection and evaluation of cerebral hypoperfusion in chronic occlusive carotid disease.",
keywords = "Brain, FAIR, HASTE, MRI, Perfusion",
author = "Kentaro Ida and Shiro Akaki and Tetsuro Sei and Masatoshi Tsunoda and Susumu Kanazawa",
year = "2006",
language = "English",
volume = "60",
pages = "215--221",
journal = "Acta Medica Okayama",
issn = "0386-300X",
publisher = "Okayama University",
number = "4",

}

TY - JOUR

T1 - Cerebral perfusion MR imaging using FAIR-HASTE in chronic carotid occlusive disease

T2 - Comparison with dynamic susceptibility contrast-perfusion MR imaging

AU - Ida, Kentaro

AU - Akaki, Shiro

AU - Sei, Tetsuro

AU - Tsunoda, Masatoshi

AU - Kanazawa, Susumu

PY - 2006

Y1 - 2006

N2 - To determine the efficacy of flow-sensitive alternating inversion recovery using half-Fourier single-shot turbo spin-echo (FAIR-HASTE) in detecting cerebral hypoperfusion in chronic carotid occlusive disease, we subjected 12 patients with various degrees of cervical internal carotid artery stenoses and/or occlusion (Stenosis group) and 24 volunteers (Normal group) to FAIR-HASTE. In addition, 10 out of 12 patients in the Stenosis group underwent dynamic susceptibility contrast-perfusion magnetic resonance imaging (DSC-pMRI) before and after revascularization in the dominantly affected side. The absolute asymmetry indexes (Als) of both cerebral hemispheres in the Normal and Stenosis groups were compared in FAIR-HASTE. In addition, the Als were compared with those in the Stenosis group before and after revascularization in both FAIR-HASTE and regional cerebral blood flow (rCBF), calculated with DSC-pMRI. A statistically significant difference was recognized between the Als in the Normal and Stenosis groups (AI = 2.25 ± 1.92, 8.09 ± 4.60, respectively; p <0.0001). Furthermore, in the Stenosis group the Als on both FAIR-HASTE (8.88 ± 4.93, 2.22 ± 1.79, respectively; p = 0.0003) and rCBF (7.13 ± 3.57, 1.25 ± 1.33, respectively; p = 0.0003) significantly decreased after revascularization. In the Stenosis group, before revascularization, signal intensity on both FAIR-HASTE and rCBF had a tendency to be lower in the dominantly affected side. FAIR-HASTE imaging was useful in the detection and evaluation of cerebral hypoperfusion in chronic occlusive carotid disease.

AB - To determine the efficacy of flow-sensitive alternating inversion recovery using half-Fourier single-shot turbo spin-echo (FAIR-HASTE) in detecting cerebral hypoperfusion in chronic carotid occlusive disease, we subjected 12 patients with various degrees of cervical internal carotid artery stenoses and/or occlusion (Stenosis group) and 24 volunteers (Normal group) to FAIR-HASTE. In addition, 10 out of 12 patients in the Stenosis group underwent dynamic susceptibility contrast-perfusion magnetic resonance imaging (DSC-pMRI) before and after revascularization in the dominantly affected side. The absolute asymmetry indexes (Als) of both cerebral hemispheres in the Normal and Stenosis groups were compared in FAIR-HASTE. In addition, the Als were compared with those in the Stenosis group before and after revascularization in both FAIR-HASTE and regional cerebral blood flow (rCBF), calculated with DSC-pMRI. A statistically significant difference was recognized between the Als in the Normal and Stenosis groups (AI = 2.25 ± 1.92, 8.09 ± 4.60, respectively; p <0.0001). Furthermore, in the Stenosis group the Als on both FAIR-HASTE (8.88 ± 4.93, 2.22 ± 1.79, respectively; p = 0.0003) and rCBF (7.13 ± 3.57, 1.25 ± 1.33, respectively; p = 0.0003) significantly decreased after revascularization. In the Stenosis group, before revascularization, signal intensity on both FAIR-HASTE and rCBF had a tendency to be lower in the dominantly affected side. FAIR-HASTE imaging was useful in the detection and evaluation of cerebral hypoperfusion in chronic occlusive carotid disease.

KW - Brain

KW - FAIR

KW - HASTE

KW - MRI

KW - Perfusion

UR - http://www.scopus.com/inward/record.url?scp=33748445903&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748445903&partnerID=8YFLogxK

M3 - Article

C2 - 16943858

AN - SCOPUS:33748445903

VL - 60

SP - 215

EP - 221

JO - Acta Medica Okayama

JF - Acta Medica Okayama

SN - 0386-300X

IS - 4

ER -