Cell proliferation on nano-structured titanium oxide layer prepared on titanium substrates

Satoshi Hayakawa, Koji Kawanishi, Yuki Shirosaki, Akiyoshi Osaka

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Effects of nanometer-scale surface roughness of titanium oxide layer on the adhesion and proliferation of osteoblast-like cell were examined. The nano-structured titanium oxide layer was prepared on titanium substrates by chemical treatment and heat-treatment. The anatase or rutile phase of titanium oxide was formed on the titanium substrates. The surface roughness of titanium oxide layer depended on the chemical treatment time or the heat-treatment time. The average roughness (Sa) was controlled in the range from 10 to 70 nm. The cell metabolic activity increased on the substrate with limited surface roughness. It is found that cell proliferation is affected by nanometer-scale surface roughness of titanium oxide layer.

Original languageEnglish
Title of host publicationCeramic Transactions
Pages205-212
Number of pages8
Volume218
Publication statusPublished - 2010
Event8th Pacific Rim Conference on Ceramic and Glass Technology, PACRIM-8 - Vancouver, BC, Canada
Duration: May 31 2009Jun 5 2009

Publication series

NameCeramic Transactions
Volume218
ISSN (Print)10421122

Other

Other8th Pacific Rim Conference on Ceramic and Glass Technology, PACRIM-8
CountryCanada
CityVancouver, BC
Period5/31/096/5/09

Fingerprint

Titanium oxides
Cell proliferation
Titanium
Surface roughness
Substrates
Heat treatment
Osteoblasts
Titanium dioxide
Adhesion
titanium dioxide

ASJC Scopus subject areas

  • Ceramics and Composites
  • Materials Chemistry

Cite this

Hayakawa, S., Kawanishi, K., Shirosaki, Y., & Osaka, A. (2010). Cell proliferation on nano-structured titanium oxide layer prepared on titanium substrates. In Ceramic Transactions (Vol. 218, pp. 205-212). (Ceramic Transactions; Vol. 218).

Cell proliferation on nano-structured titanium oxide layer prepared on titanium substrates. / Hayakawa, Satoshi; Kawanishi, Koji; Shirosaki, Yuki; Osaka, Akiyoshi.

Ceramic Transactions. Vol. 218 2010. p. 205-212 (Ceramic Transactions; Vol. 218).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hayakawa, S, Kawanishi, K, Shirosaki, Y & Osaka, A 2010, Cell proliferation on nano-structured titanium oxide layer prepared on titanium substrates. in Ceramic Transactions. vol. 218, Ceramic Transactions, vol. 218, pp. 205-212, 8th Pacific Rim Conference on Ceramic and Glass Technology, PACRIM-8, Vancouver, BC, Canada, 5/31/09.
Hayakawa S, Kawanishi K, Shirosaki Y, Osaka A. Cell proliferation on nano-structured titanium oxide layer prepared on titanium substrates. In Ceramic Transactions. Vol. 218. 2010. p. 205-212. (Ceramic Transactions).
Hayakawa, Satoshi ; Kawanishi, Koji ; Shirosaki, Yuki ; Osaka, Akiyoshi. / Cell proliferation on nano-structured titanium oxide layer prepared on titanium substrates. Ceramic Transactions. Vol. 218 2010. pp. 205-212 (Ceramic Transactions).
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