We report the cloning of a chicken Transformer 2 (Tra 2) cDNA that encodes a protein of 289 amino acids which are 97.9% identical to those of mammalian splicing factor, Tra 2. Tra 2 mRNA was expressed in chicken embryonic tissues and was observed as a band of 1.5 kb by Northern blot analysis. Whole mount in situ hybridization showed an mRNA expression of Tra 2 in telencephalon, mandible, hyoid arch, wing and leg buds as early as day 3.5 of incubation. These results suggest that the Tra 2 gene may play a role in organogenesis in the chicken embryo.
|Number of pages||4|
|Journal||Biochimica et Biophysica Acta - Gene Structure and Expression|
|Publication status||Published - Dec 12 2002|
- Transformer 2 (Tra 2)
- cDNA cloning
ASJC Scopus subject areas
- Structural Biology