Cationic surfactant changes the morphology of DNA molecules

Hisanori Nakanishi, Koji Tsuchiya, Takahiro Okubo, Hideki Sakai, Masahiko Abe

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

The effect of cetyltrimethylammonium bromide (CTAB), a cationic surfactant, was investigated on the aggregated form of DNA molecules in water at a given temperature. CTAB caused changes in the aggregated form of DNA molecules from loosely packed spherical to rodlike through toroidal one with increasing concentration below the critical micelle concentration (CMC). The change was suggested to arise from the ion complex formation between CTAB and DNA molecules due to the electrostatic interaction, thereby reducing the surface charge and solubility in water of the latter.

Original languageEnglish
Pages (from-to)345-347
Number of pages3
JournalLangmuir
Volume23
Issue number2
DOIs
Publication statusPublished - Jan 16 2007
Externally publishedYes

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry

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  • Cite this

    Nakanishi, H., Tsuchiya, K., Okubo, T., Sakai, H., & Abe, M. (2007). Cationic surfactant changes the morphology of DNA molecules. Langmuir, 23(2), 345-347. https://doi.org/10.1021/la051443p