Cardiopulmonary exercise testing after single and double lung transplantation

S. Miyoshi, E. P. Trulock, H. J. Schaefers, C. M. Hsieh, G. A. Patterson, J. D. Cooper

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

The cardiopulmonary response to exercise was investigated in six single and six double lung transplant recipients using a three-minute incremental work rate protocol on a cycle ergometer. Maximum V̇O2 averaged 44.2 ± 9.2 percent and 48.5 ± 5.0 percent of predicted maximal V̇O2 in the single and double lung transplant groups, respectively. No evidence of ventilatory limitation to exercise was found in either group. Circulatory factors that may have limited exercise capacity included anemia and submaximal heart rates. There was a strong correlation between V̇O2/kg at venous blood lactate level of 2.2 mEq/L and vital capacity/body surface area in the single, but not in the double, lung recipients. Maximum V̇O2 in these lung transplant recipients was comparable to previously published values in heart-lung transplant recipients. The factors that limit maximum exercise capacity after lung transplantation deserve further study.

Original languageEnglish
Pages (from-to)1130-1136
Number of pages7
JournalChest
Volume97
Issue number5
Publication statusPublished - 1990
Externally publishedYes

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Lung Transplantation
Exercise
Lung
Body Surface Area
Vital Capacity
Anemia
Lactic Acid
Heart Rate
Transplants
Transplant Recipients

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Miyoshi, S., Trulock, E. P., Schaefers, H. J., Hsieh, C. M., Patterson, G. A., & Cooper, J. D. (1990). Cardiopulmonary exercise testing after single and double lung transplantation. Chest, 97(5), 1130-1136.

Cardiopulmonary exercise testing after single and double lung transplantation. / Miyoshi, S.; Trulock, E. P.; Schaefers, H. J.; Hsieh, C. M.; Patterson, G. A.; Cooper, J. D.

In: Chest, Vol. 97, No. 5, 1990, p. 1130-1136.

Research output: Contribution to journalArticle

Miyoshi, S, Trulock, EP, Schaefers, HJ, Hsieh, CM, Patterson, GA & Cooper, JD 1990, 'Cardiopulmonary exercise testing after single and double lung transplantation', Chest, vol. 97, no. 5, pp. 1130-1136.
Miyoshi S, Trulock EP, Schaefers HJ, Hsieh CM, Patterson GA, Cooper JD. Cardiopulmonary exercise testing after single and double lung transplantation. Chest. 1990;97(5):1130-1136.
Miyoshi, S. ; Trulock, E. P. ; Schaefers, H. J. ; Hsieh, C. M. ; Patterson, G. A. ; Cooper, J. D. / Cardiopulmonary exercise testing after single and double lung transplantation. In: Chest. 1990 ; Vol. 97, No. 5. pp. 1130-1136.
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