Abstract
We report a case of carcinosarcoma in the transverse colon in a 60-year-old woman. She was admitted to our hospital for further examination of occult blood in October, 1995. Colonoscopy disclosed an elevated lesion with ulceration in the transverse colon, and she underwent right hemicolectomy. Histopathological examination revealed the tumor to consist of both carcinomatous and sarcomatous elements, the latter being more predominant. Immunohistochemistry revealed vimentin immunoreactivity in most of the sarcomatous cells, and S-100 and myoglobin in a few carcinomatous cells. Distinct carcinomatous features were noted in one superficial portion of the tumor, and these carcinomatous cells showed immunoreactivity for epithelial membrane antigen. The patient is alive 14 months after surgery without evidence of recurrence. To our knowledge, this is the fourth reported case of carcinosarcoma of the colon. Our review of the literature disclosed poor prognosis in colonic carcinosarcoma.
| Original language | English |
|---|---|
| Pages (from-to) | 276-279 |
| Number of pages | 4 |
| Journal | Journal of Gastroenterology |
| Volume | 33 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 1998 |
| Externally published | Yes |
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Keywords
- Carcinosarcoma
- Colon
- Immunohistochemistry
ASJC Scopus subject areas
- Gastroenterology
Cite this
Carcinosarcoma of the colon : Report of a case and review of the literature. / Nakao, Atsunori; Sakagami, Kenichi; Uda, Masashi; Mitsuoka, Shintaro; Ito, Hisao.
In: Journal of Gastroenterology, Vol. 33, No. 2, 04.1998, p. 276-279.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Carcinosarcoma of the colon
T2 - Report of a case and review of the literature
AU - Nakao, Atsunori
AU - Sakagami, Kenichi
AU - Uda, Masashi
AU - Mitsuoka, Shintaro
AU - Ito, Hisao
PY - 1998/4
Y1 - 1998/4
N2 - We report a case of carcinosarcoma in the transverse colon in a 60-year-old woman. She was admitted to our hospital for further examination of occult blood in October, 1995. Colonoscopy disclosed an elevated lesion with ulceration in the transverse colon, and she underwent right hemicolectomy. Histopathological examination revealed the tumor to consist of both carcinomatous and sarcomatous elements, the latter being more predominant. Immunohistochemistry revealed vimentin immunoreactivity in most of the sarcomatous cells, and S-100 and myoglobin in a few carcinomatous cells. Distinct carcinomatous features were noted in one superficial portion of the tumor, and these carcinomatous cells showed immunoreactivity for epithelial membrane antigen. The patient is alive 14 months after surgery without evidence of recurrence. To our knowledge, this is the fourth reported case of carcinosarcoma of the colon. Our review of the literature disclosed poor prognosis in colonic carcinosarcoma.
AB - We report a case of carcinosarcoma in the transverse colon in a 60-year-old woman. She was admitted to our hospital for further examination of occult blood in October, 1995. Colonoscopy disclosed an elevated lesion with ulceration in the transverse colon, and she underwent right hemicolectomy. Histopathological examination revealed the tumor to consist of both carcinomatous and sarcomatous elements, the latter being more predominant. Immunohistochemistry revealed vimentin immunoreactivity in most of the sarcomatous cells, and S-100 and myoglobin in a few carcinomatous cells. Distinct carcinomatous features were noted in one superficial portion of the tumor, and these carcinomatous cells showed immunoreactivity for epithelial membrane antigen. The patient is alive 14 months after surgery without evidence of recurrence. To our knowledge, this is the fourth reported case of carcinosarcoma of the colon. Our review of the literature disclosed poor prognosis in colonic carcinosarcoma.
KW - Carcinosarcoma
KW - Colon
KW - Immunohistochemistry
UR - http://www.scopus.com/inward/record.url?scp=0031891208&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031891208&partnerID=8YFLogxK
U2 - 10.1007/s005350050083
DO - 10.1007/s005350050083
M3 - Article
VL - 33
SP - 276
EP - 279
JO - Journal of Gastroenterology
JF - Journal of Gastroenterology
SN - 0944-1174
IS - 2
ER -