Abstract
The effects of intraperitoneal administration of dimethylsulfonioacetate (DMSA), dimethlsulfoniopropionate (DMSP), and methylmethionine (MeMet) solutions (10 mM each) on the body weights and the hematological parameters (red and white blood cells) of Ehrlich ascites carcinoma (EAC)-bearing mice were examined for up to 10d. Body weights significantly increased in the EAC-bearing mice treated with and without MeMet in contrast to those with DMSA and DMSP. This increase was attributed to the increased amounts of ascitic fluid. EAC-bearing mice with and without MeMet both showed abnormal values of hematological parameters, while those with DMSA and DMSP exhibited almost normal levels on the 10th day.
Original language | English |
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Pages (from-to) | 808-811 |
Number of pages | 4 |
Journal | Bioscience, Biotechnology and Biochemistry |
Volume | 75 |
Issue number | 4 |
DOIs | |
Publication status | Published - May 16 2011 |
Keywords
- Dimethylsulfonioacetate
- Dimethylsulfoniopropionate
- Ehrlich ascites carcinoma
- Methylmethionine
- Red and white blood cells
ASJC Scopus subject areas
- Biotechnology
- Analytical Chemistry
- Biochemistry
- Applied Microbiology and Biotechnology
- Molecular Biology
- Organic Chemistry