Carbonic anhydrase activity in the trigeminal primary afferent neuronal cell bodies with peripheral axons innervating tha mandibular molar tooth pulps of the rat

Tomosada Sugimoto, Motohide Takemura, Hiroyuki Ichikawa, Michio Akai

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Trigeminal primary afferent neuronal cell bodies were labeled with FITC-WGA retrogradely transported from the mandibular molar tooth pulp (tooth pulp) and the cutaneous branch of the mylohyoid nerve (cutaneous nerve) in the rat. Tissue sections were then incubated in Hansson's medium for histological demonstration of carbonic anhydrase (CA) activity. About 85% of primary neurons innervating the tooth pulp had medium to large cell bodies (≥ 300 μm2 in cross-sectional area), while 77% of those innervating the cutaneous nerve were small (<300 μm2). A total of 32% of the tooth pulp cells exhibited CA activity. CA-containing cells constituted only about 4% of the cutaneous nerve cells. In view of the known distribution of CA within the rodent nervous system, the CA-containing cells are considered to represent the tooth pulp primaries conducting in A-beta velocity range and projecting to rostral subdivisions of the brainstem sensory trigeminal nuclear complex.

Original languageEnglish
Pages (from-to)354-357
Number of pages4
JournalBrain Research
Volume505
Issue number2
Publication statusPublished - Dec 29 1989
Externally publishedYes

Fingerprint

Carbonic Anhydrases
Axons
Tooth
Skin
Trigeminal Nuclei
Neurons
Deciduous Tooth
Nervous System
Brain Stem
Rodentia
Cell Body

Keywords

  • Carbonic anhydrase
  • Primary afferent neuron
  • Tooth pulp

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology
  • Molecular Biology
  • Developmental Biology

Cite this

Carbonic anhydrase activity in the trigeminal primary afferent neuronal cell bodies with peripheral axons innervating tha mandibular molar tooth pulps of the rat. / Sugimoto, Tomosada; Takemura, Motohide; Ichikawa, Hiroyuki; Akai, Michio.

In: Brain Research, Vol. 505, No. 2, 29.12.1989, p. 354-357.

Research output: Contribution to journalArticle

Sugimoto, Tomosada ; Takemura, Motohide ; Ichikawa, Hiroyuki ; Akai, Michio. / Carbonic anhydrase activity in the trigeminal primary afferent neuronal cell bodies with peripheral axons innervating tha mandibular molar tooth pulps of the rat. In: Brain Research. 1989 ; Vol. 505, No. 2. pp. 354-357.
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