Camptothins A and B, New Dimeric Hydrolyzable Tannins from Camptotheca acuminata Decne

Tsutomu Hatano; Yukihiko Ikegami; Takuo Okuda; Tetsuro Shingu

doi:10.1248/cpb.36.2017

Camptothins A and B, New Dimeric Hydrolyzable Tannins from Camptotheca acuminata Decne

Tsutomu Hatano, Yukihiko Ikegami, Takuo Okuda, Tetsuro Shingu

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Two new hydrolyzable tannins, named camptothins A (1) and B (4), have been isolated from the leaf of Camptotheca acuminata (Nyssaceae) along with cornusiin A (2), gemin D (3), tellimagrandin I (5), tellimagrandin II (6), l,2,6-tri-O-galloyl-β-D-glucose (7) and 1,2,3,6-tetra-O-galloyl-β-D-glucose (8). Pedunculagin (9) was isolated from the fruit of C. acuminata. The dimeric structures of camptothins A and B have been established based on chemical and spectroscopic evidence.

Original language	English
Pages (from-to)	2017-2022
Number of pages	6
Journal	Chemical and Pharmaceutical Bulletin
Volume	36
Issue number	6
DOIs	https://doi.org/10.1248/cpb.36.2017
Publication status	Published - 1988

Keywords

Camptotheca acuminata
Nyssaceae
camptothin A
camptothin B
centrifugal partition chromatography
cornusiin A
dimeric hydrolyzable tannin
ellagitannin
hydrolyzable tannin
tannin

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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title = "Camptothins A and B, New Dimeric Hydrolyzable Tannins from Camptotheca acuminata Decne",

abstract = "Two new hydrolyzable tannins, named camptothins A (1) and B (4), have been isolated from the leaf of Camptotheca acuminata (Nyssaceae) along with cornusiin A (2), gemin D (3), tellimagrandin I (5), tellimagrandin II (6), l,2,6-tri-O-galloyl-β-D-glucose (7) and 1,2,3,6-tetra-O-galloyl-β-D-glucose (8). Pedunculagin (9) was isolated from the fruit of C. acuminata. The dimeric structures of camptothins A and B have been established based on chemical and spectroscopic evidence.",

keywords = "Camptotheca acuminata, Nyssaceae, camptothin A, camptothin B, centrifugal partition chromatography, cornusiin A, dimeric hydrolyzable tannin, ellagitannin, hydrolyzable tannin, tannin",

author = "Tsutomu Hatano and Yukihiko Ikegami and Takuo Okuda and Tetsuro Shingu",

year = "1988",

doi = "10.1248/cpb.36.2017",

language = "English",

volume = "36",

pages = "2017--2022",

journal = "Chemical and Pharmaceutical Bulletin",

issn = "0009-2363",

publisher = "Pharmaceutical Society of Japan",

number = "6",

}

TY - JOUR

T1 - Camptothins A and B, New Dimeric Hydrolyzable Tannins from Camptotheca acuminata Decne

AU - Hatano, Tsutomu

AU - Ikegami, Yukihiko

AU - Okuda, Takuo

AU - Shingu, Tetsuro

PY - 1988

Y1 - 1988

N2 - Two new hydrolyzable tannins, named camptothins A (1) and B (4), have been isolated from the leaf of Camptotheca acuminata (Nyssaceae) along with cornusiin A (2), gemin D (3), tellimagrandin I (5), tellimagrandin II (6), l,2,6-tri-O-galloyl-β-D-glucose (7) and 1,2,3,6-tetra-O-galloyl-β-D-glucose (8). Pedunculagin (9) was isolated from the fruit of C. acuminata. The dimeric structures of camptothins A and B have been established based on chemical and spectroscopic evidence.

AB - Two new hydrolyzable tannins, named camptothins A (1) and B (4), have been isolated from the leaf of Camptotheca acuminata (Nyssaceae) along with cornusiin A (2), gemin D (3), tellimagrandin I (5), tellimagrandin II (6), l,2,6-tri-O-galloyl-β-D-glucose (7) and 1,2,3,6-tetra-O-galloyl-β-D-glucose (8). Pedunculagin (9) was isolated from the fruit of C. acuminata. The dimeric structures of camptothins A and B have been established based on chemical and spectroscopic evidence.

KW - Camptotheca acuminata

KW - Nyssaceae

KW - camptothin A

KW - camptothin B

KW - centrifugal partition chromatography

KW - cornusiin A

KW - dimeric hydrolyzable tannin

KW - ellagitannin

KW - hydrolyzable tannin

KW - tannin

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DO - 10.1248/cpb.36.2017

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SN - 0009-2363

VL - 36

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EP - 2022

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 6

ER -

Camptothins A and B, New Dimeric Hydrolyzable Tannins from Camptotheca acuminata Decne

Abstract

Keywords

ASJC Scopus subject areas

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