Calcium-binding protein-immunoreactive innervation of the rat vibrissa

H. Ichikawa, T. Sugimoto

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Immunohistochemistry detected calcium-binding proteins (CaBPs) in corpuscular and Merkel nerve endings of the rat vibrissa. CaBP-immunoreactive (ir) corpuscular endings were divided into two types: ramified and unramified endings. Ramified endings were subdivided into reticular and Ruffini endings. Unramified endings were identical to longitudinal lanceolate endings which have been described previously. Reticular and unramified endings as well as Merkel endings co-expressed neurocalcin (NC)- and parvalbumin (PV)-immunoreactivity (ir). However, such endings were devoid of peptide 19 (PEP19)-ir. PV-ir Ruffini endings were immunoreactive for PEP19 but not NC. The retrograde tracing method revealed that 34, 21 and 18% of trigeminal neurons which project to the infraorbital nerve exhibited NC-, PEP19- and PV-ir, respectively. In addition, 73 and 36% of the PV-ir neurons showed NC- and PEP19-ir, respectively. The content and co-expression of CaBPs in vibrissal low-threshold mechanoreceptors may depend on their terminal morphology.

Original languageEnglish
Pages (from-to)226-231
Number of pages6
JournalBrain Research
Volume970
Issue number1-2
DOIs
Publication statusPublished - Apr 25 2003

Fingerprint

Neurocalcin
Vibrissae
Parvalbumins
Calcium-Binding Proteins
Peptides
Neurons
Mechanoreceptors
Nerve Endings
Immunohistochemistry

Keywords

  • Immunohistochemistry
  • Neurocalcin
  • Parvalbumin
  • Peptide 19
  • Trigeminal ganglion
  • Vibrissa

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Calcium-binding protein-immunoreactive innervation of the rat vibrissa. / Ichikawa, H.; Sugimoto, T.

In: Brain Research, Vol. 970, No. 1-2, 25.04.2003, p. 226-231.

Research output: Contribution to journalArticle

Ichikawa, H. ; Sugimoto, T. / Calcium-binding protein-immunoreactive innervation of the rat vibrissa. In: Brain Research. 2003 ; Vol. 970, No. 1-2. pp. 226-231.
@article{7e86a01dabf7405cb4d46b9b8c9a452a,
title = "Calcium-binding protein-immunoreactive innervation of the rat vibrissa",
abstract = "Immunohistochemistry detected calcium-binding proteins (CaBPs) in corpuscular and Merkel nerve endings of the rat vibrissa. CaBP-immunoreactive (ir) corpuscular endings were divided into two types: ramified and unramified endings. Ramified endings were subdivided into reticular and Ruffini endings. Unramified endings were identical to longitudinal lanceolate endings which have been described previously. Reticular and unramified endings as well as Merkel endings co-expressed neurocalcin (NC)- and parvalbumin (PV)-immunoreactivity (ir). However, such endings were devoid of peptide 19 (PEP19)-ir. PV-ir Ruffini endings were immunoreactive for PEP19 but not NC. The retrograde tracing method revealed that 34, 21 and 18{\%} of trigeminal neurons which project to the infraorbital nerve exhibited NC-, PEP19- and PV-ir, respectively. In addition, 73 and 36{\%} of the PV-ir neurons showed NC- and PEP19-ir, respectively. The content and co-expression of CaBPs in vibrissal low-threshold mechanoreceptors may depend on their terminal morphology.",
keywords = "Immunohistochemistry, Neurocalcin, Parvalbumin, Peptide 19, Trigeminal ganglion, Vibrissa",
author = "H. Ichikawa and T. Sugimoto",
year = "2003",
month = "4",
day = "25",
doi = "10.1016/S0006-8993(03)02292-3",
language = "English",
volume = "970",
pages = "226--231",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",
number = "1-2",

}

TY - JOUR

T1 - Calcium-binding protein-immunoreactive innervation of the rat vibrissa

AU - Ichikawa, H.

AU - Sugimoto, T.

PY - 2003/4/25

Y1 - 2003/4/25

N2 - Immunohistochemistry detected calcium-binding proteins (CaBPs) in corpuscular and Merkel nerve endings of the rat vibrissa. CaBP-immunoreactive (ir) corpuscular endings were divided into two types: ramified and unramified endings. Ramified endings were subdivided into reticular and Ruffini endings. Unramified endings were identical to longitudinal lanceolate endings which have been described previously. Reticular and unramified endings as well as Merkel endings co-expressed neurocalcin (NC)- and parvalbumin (PV)-immunoreactivity (ir). However, such endings were devoid of peptide 19 (PEP19)-ir. PV-ir Ruffini endings were immunoreactive for PEP19 but not NC. The retrograde tracing method revealed that 34, 21 and 18% of trigeminal neurons which project to the infraorbital nerve exhibited NC-, PEP19- and PV-ir, respectively. In addition, 73 and 36% of the PV-ir neurons showed NC- and PEP19-ir, respectively. The content and co-expression of CaBPs in vibrissal low-threshold mechanoreceptors may depend on their terminal morphology.

AB - Immunohistochemistry detected calcium-binding proteins (CaBPs) in corpuscular and Merkel nerve endings of the rat vibrissa. CaBP-immunoreactive (ir) corpuscular endings were divided into two types: ramified and unramified endings. Ramified endings were subdivided into reticular and Ruffini endings. Unramified endings were identical to longitudinal lanceolate endings which have been described previously. Reticular and unramified endings as well as Merkel endings co-expressed neurocalcin (NC)- and parvalbumin (PV)-immunoreactivity (ir). However, such endings were devoid of peptide 19 (PEP19)-ir. PV-ir Ruffini endings were immunoreactive for PEP19 but not NC. The retrograde tracing method revealed that 34, 21 and 18% of trigeminal neurons which project to the infraorbital nerve exhibited NC-, PEP19- and PV-ir, respectively. In addition, 73 and 36% of the PV-ir neurons showed NC- and PEP19-ir, respectively. The content and co-expression of CaBPs in vibrissal low-threshold mechanoreceptors may depend on their terminal morphology.

KW - Immunohistochemistry

KW - Neurocalcin

KW - Parvalbumin

KW - Peptide 19

KW - Trigeminal ganglion

KW - Vibrissa

UR - http://www.scopus.com/inward/record.url?scp=0037466344&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037466344&partnerID=8YFLogxK

U2 - 10.1016/S0006-8993(03)02292-3

DO - 10.1016/S0006-8993(03)02292-3

M3 - Article

C2 - 12706265

AN - SCOPUS:0037466344

VL - 970

SP - 226

EP - 231

JO - Brain Research

JF - Brain Research

SN - 0006-8993

IS - 1-2

ER -