CRSP is a member of the calcitonin gene-related peptide (CGRP) family and consists of a single intramolecular ring structure and amidated C-terminus, which are common to family members. More than three types of CRSPs are present in pigs, dogs, cattle, goats, sheep, and horses, but not in humans, rats or mice. Porcine CRSP-1 binds to calcitonin receptor to decrease food intake, plasma calcium level, and locomotion activity in rats. CRSP is the most recently identified peptide of the CGRP family; therefore, large parts of its biological functions remain unclear.
|Title of host publication||Handbook of Hormones|
|Subtitle of host publication||Comparative Endocrinology for Basic and Clinical Research|
|Publication status||Published - Jan 1 2015|
- calcitonin receptor
- central nervous system
- CGRP family
ASJC Scopus subject areas