Calcein leakage behavior from vesicles induced by proteinvesicle interaction: A study by surface pressurearea isotherms

Saki Fukuma, Toshinori Shimanouchi, Keita Hayashi, Yukitaka Kimura

Research output: Contribution to journalArticle

Abstract

The release behavior of substrates encapsulated in the vesicle can be controlled by the interaction between the vesicular membrane and the protein. However, its control mechanism is still now unknown. Therefore, the proteinvesicle interaction was investigated by a A isotherm. It was clarified that the released amount of encapsulated substrates increased with increasing proteinvesicle interaction. This result leads to the development of drug delivery systems (DDS) and of biosensor technology.

Original languageEnglish
Pages (from-to)1036-1039
Number of pages4
JournalChemistry Letters
Volume46
Issue number7
DOIs
Publication statusPublished - 2017

Keywords

  • Calcein leakage
  • Protein
  • Vesicle

ASJC Scopus subject areas

  • Chemistry(all)

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