Calcein leakage behavior from vesicles induced by proteinvesicle interaction: A study by surface pressurearea isotherms

Saki Fukuma; Toshinori Shimanouchi; Keita Hayashi; Yukitaka Kimura

doi:10.1246/cl.170119

Calcein leakage behavior from vesicles induced by proteinvesicle interaction: A study by surface pressurearea isotherms

Saki Fukuma, Toshinori Shimanouchi, Keita Hayashi, Yukitaka Kimura

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

The release behavior of substrates encapsulated in the vesicle can be controlled by the interaction between the vesicular membrane and the protein. However, its control mechanism is still now unknown. Therefore, the proteinvesicle interaction was investigated by a A isotherm. It was clarified that the released amount of encapsulated substrates increased with increasing proteinvesicle interaction. This result leads to the development of drug delivery systems (DDS) and of biosensor technology.

Original language	English
Pages (from-to)	1036-1039
Number of pages	4
Journal	Chemistry Letters
Volume	46
Issue number	7
DOIs	https://doi.org/10.1246/cl.170119
Publication status	Published - 2017

Keywords

Calcein leakage
Protein
Vesicle

ASJC Scopus subject areas

Chemistry(all)

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10.1246/cl.170119

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abstract = "The release behavior of substrates encapsulated in the vesicle can be controlled by the interaction between the vesicular membrane and the protein. However, its control mechanism is still now unknown. Therefore, the proteinvesicle interaction was investigated by a A isotherm. It was clarified that the released amount of encapsulated substrates increased with increasing proteinvesicle interaction. This result leads to the development of drug delivery systems (DDS) and of biosensor technology.",

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AU - Kimura, Yukitaka

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