c-fos induction in the subnucleus oralis following trigeminal nerve stimulation

Tomosada Sugimoto, Yi Fen He, Chun Xiao, Hiroyuki Ichikawa

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Neurons with c-Fos protein-like immunoreactivity (fos-neurons) were examined in the rostral parts of the brainstem sensory trigeminal nuclear complex following intense electrical stimulation of the trigeminal nerves and noxious mechanical stimulation of the trigeminal receptive fields. Stimulation of all the examined nerves and receptive fields induced some fos- neurons at the medial edge of the subnucleus interpolaris but not in the principal sensory trigeminal nucleus. Stimulation of the primary neurons innervating the intraoral structures but not facial skin induced fos-neurons in the ipsilateral subnucleus oralis. These oralis fos-neurons were located in the dorsomedial nucleus that contained calcitonin gene-related peptide- like immunoreactivity. The oralis fos-neurons are considered to be involved in the processing of intraoral nociceptive signals.

Original languageEnglish
Pages (from-to)158-162
Number of pages5
JournalBrain Research
Volume783
Issue number1
DOIs
Publication statusPublished - Feb 2 1998

Fingerprint

Trigeminal Nerve
Neurons
Trigeminal Nuclei
Proto-Oncogene Proteins c-fos
Mediodorsal Thalamic Nucleus
Calcitonin Gene-Related Peptide
Electric Stimulation
Brain Stem
Skin

Keywords

  • c-fos
  • Cutaneous nerve
  • Intraoral nerve
  • Spinal trigeminal tract nucleus
  • Subnucleus oralis

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

c-fos induction in the subnucleus oralis following trigeminal nerve stimulation. / Sugimoto, Tomosada; He, Yi Fen; Xiao, Chun; Ichikawa, Hiroyuki.

In: Brain Research, Vol. 783, No. 1, 02.02.1998, p. 158-162.

Research output: Contribution to journalArticle

Sugimoto, Tomosada ; He, Yi Fen ; Xiao, Chun ; Ichikawa, Hiroyuki. / c-fos induction in the subnucleus oralis following trigeminal nerve stimulation. In: Brain Research. 1998 ; Vol. 783, No. 1. pp. 158-162.
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