Bronchiolitis obliterans organizing pneumonia (BOOP) in a case of smouldering adult T-cell leukaemia

Kiyoshi Matsuo, Shinya Tada, Mikio Kataoka, Arihiko Kanehiro, Saori Kaneko, Toshitsugu Miyake, Ichiro Yamadori, Mine Harada

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Although various respiratory diseases have been reported in human T lymphotropic virus type-1 (HTLV-1) carriers or patients with adult T-cell leukaemia (ATL), there appears to be no report of the development of bronchiolitis obliterans organizing pneumonia (BOOP) in ATL or HTLV-1-related disorders. We describe a 51-year-old male with smouldering ATL who developed BOOP during a long-term follow up. Bronchoalveolar lavage (BAL) and transbronchial lung biopsy (TBLB) were performed in the right lower lobe B6 with infiltrative shadows. As a result of flow cytometric analysis of peripheral lymphocytes and BAL lymphocytes, histological examination of the biopsied lung specimen, and the clinical course, we excluded the pulmonary infiltration of ATL cells and bacterial infection. Thus, he was diagnosed as having BOOP and successfully treated with corticosteroid therapy. This is probably the first report of BOOP developing in ATL. Bronchiolitis obliterans organizing pneumonia should be considered in the differential diagnosis of pulmonary complications in HTLV-1 carriers or ATL patients since BOOP can be successfully treated by corticosteroids.

Original languageEnglish
Pages (from-to)81-85
Number of pages5
JournalRespirology
Volume5
Issue number1
DOIs
Publication statusPublished - 2000

Fingerprint

Cryptogenic Organizing Pneumonia
Adult T Cell Leukemia Lymphoma
Human T-lymphotropic virus 1
Lung
Bronchoalveolar Lavage
Adrenal Cortex Hormones
Lymphocytes
Bacterial Infections
Differential Diagnosis
Biopsy

Keywords

  • Adult T-cell leukaemia (ATL)
  • Bronchiolitis obliterans organizing pneumonia (BOOP)
  • Bronchoalveolar lavage (BAL)
  • Corticosteroid therapy

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Matsuo, K., Tada, S., Kataoka, M., Kanehiro, A., Kaneko, S., Miyake, T., ... Harada, M. (2000). Bronchiolitis obliterans organizing pneumonia (BOOP) in a case of smouldering adult T-cell leukaemia. Respirology, 5(1), 81-85. https://doi.org/10.1046/j.1440-1843.2000.00231.x

Bronchiolitis obliterans organizing pneumonia (BOOP) in a case of smouldering adult T-cell leukaemia. / Matsuo, Kiyoshi; Tada, Shinya; Kataoka, Mikio; Kanehiro, Arihiko; Kaneko, Saori; Miyake, Toshitsugu; Yamadori, Ichiro; Harada, Mine.

In: Respirology, Vol. 5, No. 1, 2000, p. 81-85.

Research output: Contribution to journalArticle

Matsuo, K, Tada, S, Kataoka, M, Kanehiro, A, Kaneko, S, Miyake, T, Yamadori, I & Harada, M 2000, 'Bronchiolitis obliterans organizing pneumonia (BOOP) in a case of smouldering adult T-cell leukaemia', Respirology, vol. 5, no. 1, pp. 81-85. https://doi.org/10.1046/j.1440-1843.2000.00231.x
Matsuo, Kiyoshi ; Tada, Shinya ; Kataoka, Mikio ; Kanehiro, Arihiko ; Kaneko, Saori ; Miyake, Toshitsugu ; Yamadori, Ichiro ; Harada, Mine. / Bronchiolitis obliterans organizing pneumonia (BOOP) in a case of smouldering adult T-cell leukaemia. In: Respirology. 2000 ; Vol. 5, No. 1. pp. 81-85.
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